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How do proteins efficiently and precisely shift from one conformation to another? Gardino et al. (2009) show that transient hydrogen bonds are critical to the conformational transition of the nitrogen regulatory protein NtrC between its native state and its active state.

Citation

David D Boehr. During transitions proteins make fleeting bonds. Cell. 2009 Dec 11;139(6):1049-51

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PMID: 20005798

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