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Direct cyanation of indole derivatives has been achieved with nontoxic K(4)[Fe(CN)(6)] as cyanating agent through Pd-catalyzed C-H bond activation.

Citation

Guobing Yan, Chunxiang Kuang, Yan Zhang, Jianbo Wang. Palladium-catalyzed direct cyanation of indoles with K(4)[Fe(CN)(6)]. Organic letters. 2010 Mar 5;12(5):1052-5

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PMID: 20141185

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