Correlation Engine 2.0
Clear Search sequence regions


Two new 2-arylbenzofuran neolignans and a new benzophenanthridine alkaloid, together with six known benzophenanthridine alkaloids, namely, decarine, norchelerythrine, dihydrochelerythrine, 6-acetonyldihydrochelerythrine, tridecanonchelerythrine, and 6-acetonyldihydronitidine, have been isolated from the MeOH extract of the roots of Zanthoxylum capense. Their structures were elucidated by means of spectroscopic techniques including 2D NMR experiments. All the isolated compounds were evaluated for their in vitro antibacterial activity against gram-positive and gram-negative bacteria. Some compounds showed significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 μg/mL. © Georg Thieme Verlag KG Stuttgart · New York.

Citation

Xuan Luo, Liliana Pedro, Vladimir Milic, Silva Mulhovo, Aida Duarte, Noélia Duarte, Maria-José U Ferreira. Antibacterial benzofuran neolignans and benzophenanthridine alkaloids from the roots of Zanthoxylum capense. Planta medica. 2012 Jan;78(2):148-53

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 22002848

View Full Text