Correlation Engine 2.0
Clear Search sequence regions


Sizes of these terms reflect their relevance to your search.

An efficient asymmetric Michael addition of cyclic ketones to β-nitrostyrenes using secondary diamine as an organocatalyst derived from l-proline and (R)-α-methylbenzyl amine has been described. This pyrrolidine based catalyst 1 was found to be very effective to synthesize various γ-nitrocarbonyl compounds in good yield (up to 81%) with excellent stereoselectivity (up to >99:1 dr and >99% ee). Copyright © 2012 Elsevier Ltd. All rights reserved.

Citation

Kamal Nain Singh, Paramjit Singh, Pushpinder Singh, Nand Lal, Sandeep Kumar Sharma. Pyrrolidine based chiral organocatalyst for efficient asymmetric Michael addition of cyclic ketones to β-nitrostyrenes. Bioorganic & medicinal chemistry letters. 2012 Jul 1;22(13):4225-8

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 22672804

View Full Text