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Extravasation is the diffusion of a product injected intravenously into the perivascular or subcutaneous spaces. Skin necrosis of iatrogenic origin can be observed for example with a subcutaneous perfusion of solution containing potassium chloride or the extravasation of 30% hypertonic glucose serum. Whenever a product is injected, the administration route for which the product has obtained marketing authorisation must be respected and a perfusion time of at least 4 to 5 hours per litre of solution perfused must be observed.

Citation

Soumaya Ikhefoulma, Abelhamid Mahiou, Isabelle Perillat. Skin necrosis resulting from the extravasation of intravenous injections]. Soins; la revue de référence infirmière. 2012 Sep(768):22-4

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PMID: 23115921

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