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The synthesis in 1985 by the group led by Tony McKervey of numerous calix[4]arene derivatives capable of acting as neutral, multidentate ligands proved to be a seminal step in the development of various applications of calixarenes as metal-ion binding agents.

Citation

Jack Harrowfield. Calixarenes and cations. Chemical communications (Cambridge, England). 2013 Feb 25;49(16):1578-80

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PMID: 23341187

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