Correlation Engine 2.0
Clear Search sequence regions


Wheat stem rust, caused by the fungus Puccinia graminis f. sp. tritici, afflicts bread wheat (Triticum aestivum). New virulent races collectively referred to as "Ug99" have emerged, which threaten global wheat production. The wheat gene Sr33, introgressed from the wild relative Aegilops tauschii into bread wheat, confers resistance to diverse stem rust races, including the Ug99 race group. We cloned Sr33, which encodes a coiled-coil, nucleotide-binding, leucine-rich repeat protein. Sr33 is orthologous to the barley (Hordeum vulgare) Mla mildew resistance genes that confer resistance to Blumeria graminis f. sp. hordei. The wheat Sr33 gene functions independently of RAR1, SGT1, and HSP90 chaperones. Haplotype analysis from diverse collections of Ae. tauschii placed the origin of Sr33 resistance near the southern coast of the Caspian Sea.

Citation

Sambasivam Periyannan, John Moore, Michael Ayliffe, Urmil Bansal, Xiaojing Wang, Li Huang, Karin Deal, Mingcheng Luo, Xiuying Kong, Harbans Bariana, Rohit Mago, Robert McIntosh, Peter Dodds, Jan Dvorak, Evans Lagudah. The gene Sr33, an ortholog of barley Mla genes, encodes resistance to wheat stem rust race Ug99. Science (New York, N.Y.). 2013 Aug 16;341(6147):786-8

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 23811228

View Full Text