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An efficient aziridine ring expansion cascade of cinnamylaziridine has been developed. N-Bromosuccinimide was used as the promoter. The resulting functionalized pyrrolidines are the fundamental units of many useful molecules.

Citation

Jing Zhou, Ying-Yeung Yeung. Diastereoselective synthesis of functionalized pyrrolidines through N-bromosuccinimide-induced aziridine ring expansion cascade of cinnamylaziridine. Organic & biomolecular chemistry. 2014 Oct 14;12(38):7482-5

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PMID: 25156246

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