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The epigenetic landscape of Alzheimer's disease.
Jenny Lord, Carlos Cruchaga
Nature neuroscience 2014 Sep
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Two independent epigenome-wide association studies of Alzheimer’s disease cohorts have identified overlapping methylation signals in four loci, ANK1, RPL13, RHBDF2 and CDH23, not previously associated with Alzheimer’s disease. These studies also suggest that epigenetic changes contribute more to Alzheimer’s disease than expected.
Citation
Jenny Lord, Carlos Cruchaga.
The epigenetic landscape of Alzheimer's disease.
Nature neuroscience.
2014 Sep;17(9):1138-40
Mesh Tags
Adaptor Proteins, Signal Transducing
Alzheimer Disease
Ankyrins
Carrier Proteins
Cerebral Cortex
DNA Methylation
Female
Humans
Intracellular Signaling Peptides and Proteins
Male
Nuclear Proteins
Tumor Suppressor Proteins
Substances
ANK1 protein, human
Adaptor Proteins, Signal Transducing
Ankyrins
BIN1 protein, human
Carrier Proteins
Intracellular Signaling Peptides and Proteins
Nuclear Proteins
RHBDF2 protein, human
Tumor Suppressor Proteins
PMID: 25157507
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