Chemical Composition of the Essential Oil from the Fresh Fruits of Xylopia laevigata and its Cytotoxic Evaluation.

Emmanoel Vilaça Costa, Thanany Brasil da Silva, Cinara Oliveira D'Souza Costa, Milena Botelho Pereira Soares, Daniel Pereira Bezerra

Natural product communications 2016 Mar

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The essential oil obtained by hydrodistillation from the fresh fruits of Xylopia laevigata was analyzed by gas chromatography using a flame ionization detector (GC-FID) coupled to a mass spectrometer (GC-MS). Monoterpenes predominated, forming 95.0% of the total essential oil. The major constituents identified were limonene (56.2%), α-pinene (28.0%), and β-pinene (5.5%). Cytotoxic activity against tumor cell lines and non-tumor cells was also investigated; however, neither the essential oil nor its major constituents evaluated presented any cytotoxic activity (IC₅₀ > 25.0 µg mL⁻¹).

Citation

Emmanoel Vilaça Costa, Thanany Brasil da Silva, Cinara Oliveira D'Souza Costa, Milena Botelho Pereira Soares, Daniel Pereira Bezerra. Chemical Composition of the Essential Oil from the Fresh Fruits of Xylopia laevigata and its Cytotoxic Evaluation. Natural product communications. 2016 Mar;11(3):417-8