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    Prostate cancer bone metastases usually appear as osteosclerotic lesions. However, atypical lesions have also been described. We report herein the case of a 65-year-old man treated since 2013 for prostate cancer with early bone metastases. This asymptomatic patient was referred for 18F-choline PET/CT due to a major elevation of prostate-specific antigen to >1500 ng/mL. The results indicated multiple bone lesions, disseminated on the axial skeleton, girdles, and upper extremities of femurs. Interestingly, we described the development of an intensely hypermetabolic spiculated periosteal reaction, evidencing a rapidly progressive disease. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

    Citation

    Nicolas De Leiris, Valentin Ruggeri, Laurent Riou, Mathieu Laramas, Loïc Djaileb. Aggressive Bone Metastatic Prostate Cancer With Periosteal Reaction in 18F-Choline PET/CT. Clinical nuclear medicine. 2021 Feb 01;46(2):e116-e117

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    PMID: 33181748

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