The CROWN study suggests that lorlatinib is effective in patients newly diagnosed with advanced ALK-positive non-small cell lung cancer. In the phase III trial, patients treated with lorlatinib were twice as likely to be alive without disease progression after 1 year than those who received crizotinib-with slower progression of brain metastases. ©2020 American Association for Cancer Research.
Lorlatinib Outperforms Crizotinib in NSCLC. Cancer discovery. 2021 Jan;11(1):OF5
PMID: 33298467
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