A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect on platelet function and bleeding diathesis.
Verónica Palma-Barqueros, Marilena Crescente, María Eugenia de la Morena, Melissa V Chan, Elena Almarza, Nuria Revilla, Natalia Bohdan, Antonia Miñano, José Padilla, Harriet E Allan, Tania Maffucci, Matthew L Edin, Darryl C Zeldin, Cristina Mesa-Nuñez, Carlos Damian, Ana Marín-Quilez, Rocío Benito, Irene Martínez-Martínez, Nuria Bermejo, Ignacio Casas-Aviles, Agustín Rodríguez-Alen, José R González-Porras, Jesús María Hernández-Rivas, Vicente Vicente, Javier Corral, María L Lozano, Timothy D Warner, José María Bastida, José Rivera
American journal of hematology 2021 Mar 01No abstract available.
Citation
Verónica Palma-Barqueros, Marilena Crescente, María Eugenia de la Morena, Melissa V Chan, Elena Almarza, Nuria Revilla, Natalia Bohdan, Antonia Miñano, José Padilla, Harriet E Allan, Tania Maffucci, Matthew L Edin, Darryl C Zeldin, Cristina Mesa-Nuñez, Carlos Damian, Ana Marín-Quilez, Rocío Benito, Irene Martínez-Martínez, Nuria Bermejo, Ignacio Casas-Aviles, Agustín Rodríguez-Alen, José R González-Porras, Jesús María Hernández-Rivas, Vicente Vicente, Javier Corral, María L Lozano, Timothy D Warner, José María Bastida, José Rivera. A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect on platelet function and bleeding diathesis. American journal of hematology. 2021 Mar 01;96(3):E83-E88
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PMID: 33326144
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