Correlation Engine 2.0
Clear Search sequence regions


  • free (3)
  • humans (1)
  • hydroxyl (1)
  • organoselenium compounds (6)
  • oxygen (1)
  • redox (1)
  • Sizes of these terms reflect their relevance to your search.

    Antioxidant activity of organoselenium compounds belonging to different classes i.e. functionalized aliphatic, aromatic and cyclic selenoethers, are compared on the basis of their ability to scavenge reactive oxygen species like hydroxyl and peroxyl radicals and to exhibit glutathione peroxidase (GPx) like catalytic activity. The comparative analysis has revealed that the antioxidant activity of the organoselenium compounds show direct correlation with the energy of the highest occupied molecular orbital (HOMO) and neighboring group participation that stabilizes the reaction intermediate. Finally, structural features responsible for improving the rate of reaction of organoselenium compounds with free radical/molecular oxidants have been discussed on the basis of the compounds screened at our institute.

    Citation

    Beena G Singh, Amit Kunwar. Redox reactions of organoselenium compounds: Implication in their biological activity. Free radical research. 2021 Jun;55(6):641-654

    Expand section icon Mesh Tags

    Expand section icon Substances


    PMID: 33555213

    View Full Text