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Enhancer reprogramming lies at the heart of dynamic cellular processes such as differentiation and tumorigenesis. WNT signaling is an evolutionary conserved pathway that exploits transcriptional enhancers to control the state-specific transcriptional program. Recent evidences suggest several mechanisms that govern this state-specific enhancer regulation in stem cells and cancer. Copyright © 2021 Elsevier Ltd. All rights reserved.

Citation

Fatemeh Mirzadeh Azad, Yaser Atlasi. WNT-Regulated Transcriptional Enhancers and Stem Cell Plasticity. Trends in cell biology. 2021 Jul;31(7):525-528

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PMID: 33775538

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