Correlation Engine 2.0
Clear Search sequence regions


Sizes of these terms reflect their relevance to your search.

Quality of the 68Ga solution eluted from a 68Ge/68Ga generator (Galli Eo®) was evaluated. Elution was performed 488 times from 21 to 484 days (ca. 15 months) after the calibration date. The eluted 68Ga activity was 329 MBq to 1,148 MBq, which decreased with the decay of 68Ge, but no significant change was observed in the elution yields (62.8±2.2%). The half-life of the eluted radioactivity was 67.8±0.1 min, the radionuclide purity of 68Ga was ≥99.9%, the 68Ge breakthrough was 0.000024 ±0.000004%, and the radiochemical purity of 68Ga3+ was 99.7±0.2%. Fe and Zn were detected as metal impurities in the eluent, but both were ≤10 μg/GBq. The endotoxin concentration of the eluate was ≤5 EU/mL, and the eluent passed the sterility test. These results show that the generator can stably provide 68Ga solution over a 15-month period.

Citation

Sho Tomita, Kei Higashikawa, Satoshi Ueno, Yuki Mizuno, Shusaku Tazawa, Yuji Kuge. Long-term Quality Control Test of a 68Ge/68Ga Generator]. Kaku igaku. The Japanese journal of nuclear medicine. 2021;58(1):47-58

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 34108303

View Full Text