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Epilepsy is a chronic neurological disorder that is characterized by episodes of seizure. In this study, patients with status epilepticus in the Intensive Care Unit of the Department of Neurology of Qujing First People's Hospital were collected and treated with levetiracetam injection, continuous bedside EEG monitoring (cEEG) technology, and quantitative EEG (qEEG) technique. The inhibitory effects of different doses of levetiracetam injection and sodium valproate on abnormal discharge, the improvement of clinical symptoms, the incidence of adverse reactions, and prognosis were monitored, analyzed, and compared. Compared with the experimental group of sodium valproate, 1000 mg/d levetiracetam group and 1500 mg/d levetiracetam group had a high probability of successful symptom control and a short control time. The patients had a low recurrence rate and a long recurrence time, and the probability of abnormal discharge in EEG was low. The recording results showed that levetiracetam could significantly inhibit the abnormal discharge of patients. Compared with sodium valproate, high-dose levetiracetam is a drug with a rapid effect, good effect, and long action time. Copyright © 2022 Haohao Wu et al.

Citation

Haohao Wu, Jia Liu, Fang Qian, Junsu Yang, Yue Wang, Shaoyong Guan. Clinical Evaluation of Levetiracetam in the Treatment of Epilepsy. Journal of healthcare engineering. 2022;2022:3789516

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PMID: 35422974

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