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When tested in a series of immunopharmacologic assays, the interferon inducer, WY-15297, was shown to lack activity in early vascular and humoral phases of the inflammatory response, while it was quite effective against the immunologic phase. The profile of activity of Wy-15927 was, however, unlike those previously described for reference antiinflammatory and immunosuppressive drugs and this may represent one of a new class of immunopharmacologic agents capable of selectively modulating the lymphoreticular system.

Citation

M E Rosenthale, A A Santilli, A C Scotese, S C Bell, B A Rubin. Immunopharmacologic properties of 1,6-bis[2-(diethylamino)ethoxy]xanthen-9-one dihydrochloride (Wy-15297). Journal of immunopharmacology. 1980;2(2):257-77

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PMID: 6821553

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