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QuickView for 5-HT1D receptor (compound)
| Name: | Receptor, Serotonin, 5-HT1D |
|---|---|
| Description: | A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect. |
| Synonyms: |
5 Hydroxytryptamine1D Receptor; Receptor, 5-Hydroxytryptamine1D; Receptor, Serotonin 1D; Receptors, Serotonin 1D; Receptor, 5-HT1D; 5-HT(1D) Receptor; 5-Hydroxytryptamine1D Receptor; Serotonin 1D Receptors; 5-HT1D Receptor; Serotonin 1D Receptor.
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