QuickView for AARS2;jsessionid=59A04712DA58A6C5D6F796FFCDFDE964 (gene)
- Gene Symbol:
- AARS2
Homo sapiens - Full name:
- alanyl-tRNA synthetase 2, mitochondrial
- Synonyms:
- AARSL, COXPD8, LKENP, MT-ALARS, MTALARS, alanine--tRNA ligase, mitochondrial, alanine tRNA ligase 2, mitochondrial (putative), alanyl-tRNA synthetase 2, mitochondrial (putative), alanyl-tRNA synthetase like, probable alanyl-tRNA synthetase, mitochondrial
- Genomic Location:
- Chr 6: 44374441-44389041
- Description:
-
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxid...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
6p21.1
GO Molecular Function
cation binding | carboxylic acid binding | nucleic acid binding | ribonucleotide binding | tRNA binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | aminoacyl-tRNA ligase activity | ATP binding | anion binding | adenyl nucleotide binding | amino acid binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | ligase activity | alanine-tRNA ligase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | organic acid binding | metal ion binding | heterocyclic compound binding | small molecule binding | RNA binding
GO Biological Process
RNA metabolic process | RNA processing | tRNA modification | tRNA aminoacylation | cellular process | cellular amino acid metabolic process | organic cyclic compound metabolic process | mitochondrial respiratory chain complex assembly | cellular aromatic compound metabolic process | cellular component organization | RNA modification | peptide biosynthetic process | mitochondrial translation | cellular nitrogen compound biosynthetic process | ncRNA processing | cellular nitrogen compound metabolic process | cellular component assembly | cellular biosynthetic process | mitochondrion organization | macromolecule modification | nitrogen compound metabolic process | alanyl-tRNA aminoacylation | small molecule metabolic process | cellular amide metabolic process | tRNA aminoacylation for protein translation | translation | tRNA aminoacylation for mitochondrial protein translation | biosynthetic process | cellular protein-containing complex assembly | peptide metabolic process | tRNA processing | carboxylic acid metabolic process | tRNA metabolic process | protein-containing complex assembly | protein metabolic process | metabolic process | mitochondrial gene expression | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | amide biosynthetic process | organic acid metabolic process | cellular protein metabolic process | cellular macromolecule biosynthetic process | organelle organization | ncRNA metabolic process | heterocycle metabolic process | cellular metabolic process | mitochondrial RNA metabolic process | mitochondrial alanyl-tRNA aminoacylation | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | intracellular
