Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for ABCB1 (gene)


Gene Symbol:
Abcb1a Rattus norvegicus Rattus norvegicus
Full name:
ATP binding cassette subfamily B member 1A
Synonyms:
Abcb1, Mdr1a, ATP binding cassette subfamily B member 1A, ATP binding cassette subfamily B member 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1A, ATP-binding cassette, subfamily B (MDR/TAP), member 1A, multiple drug resistant 1a
Genomic Location:
Chr 4: 21709855-21796628
Description:
ATP-binding cassette (ABC) multiple drug transporter P-glycoprotein that is activated during liver regeneration and hepatocarcinogenesis
Orthologs:
Homo sapiens Mus musculus D. melanogaster Macaca mulatta Schizosaccharomyces pombe Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_133401
XM_006235994
Protein Names
Q9JK64



GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | phosphatidylcholine-translocating ATPase activity | xenobiotic transmembrane transporter activity | ribonucleotide binding | phosphatidylethanolamine transporter activity | transmembrane transporter activity | sphingolipid transporter activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | phospholipid transporter activity | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | phosphatidylcholine transporter activity | ion binding | organic cyclic compound binding | drug transmembrane transporter activity | purine ribonucleoside triphosphate binding | protein binding | phosphatidylethanolamine-translocating ATPase activity | ceramide-translocating ATPase activity | ceramide transporter activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | xenobiotic transmembrane transporting ATPase activity | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | phospholipid-translocating ATPase activity

GO Biological Process

response to cyclosporin A | response to extracellular stimulus | brain development | cellular response to borneol | response to nutrient levels | hyperosmotic response | positive regulation of ion transmembrane transporter activity | response to lipopolysaccharide | developmental process involved in reproduction | regulation of localization | response to isoquinoline alkaloid | carbohydrate export | lipid transport | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | response to hormone | negative regulation of cellular process | phosphatidylcholine-translocating ATPase activity | response to dexamethasone | response to metal ion | cell differentiation | organic cation transport | nervous system development | cellular response to extracellular stimulus | response to drug | xenobiotic transmembrane transporter activity | membrane organization | response to antibiotic | cellular process | secretion | response to morphine | establishment of blood-brain barrier | localization | ceramide translocation | reproductive system development | response to estradiol | anion transport | regulation of digestive system process | macromolecule localization | regulation of response to osmotic stress | response to hypoxia | response to inorganic substance | regulation of membrane lipid distribution | response to peptide hormone | cellular hyperosmotic salinity response | regulation of cellular process | phosphatidylethanolamine transporter activity | cellular response to lipid | transmembrane transporter activity | cellular response to external biotic stimulus | cellular response to organonitrogen compound | sphingolipid transporter activity | cellular component organization | drug export | head development | response to stimulus | regulation of chloride transport | response to salt stress | cellular response to xenobiotic stimulus | response to stress | regulation of response to drug | sphingolipid translocation | drug transport across blood-brain barrier | response to peptide | circadian rhythm | response to L-glutamate | reproduction | rhythmic process | response to molecule of bacterial origin | cellular response to toxic substance | cellular response to organic cyclic compound | response to vitamin D | response to mycotoxin | response to nitrogen compound | cellular response to hormone stimulus | response to external biotic stimulus | system development | cellular response to nutrient levels | response to oxygen levels | reproductive process | response to flavonoid | cellular response to antibiotic | multicellular organism development | response to amino acid | mammary gland development | phospholipid transporter activity | regulation of intestinal absorption | regulation of hormone levels | stem cell proliferation | organic substance transport | response to ketone | cellular response to stress | response to lipid | cell cycle | digestive system process | regulation of anion channel activity | response to ammonium ion | positive regulation of ion transmembrane transport | active transmembrane transporter activity | response to corticosteroid | response to nutrient | cellular response to alkaloid | intestinal absorption | cell proliferation | response to cadmium ion | response to osmotic stress | G2/M transition of mitotic cell cycle | cellular response to glucocorticoid stimulus | organic anion transport | response to vitamin A | ceramide transport | phosphatidylcholine transporter activity | response to toxic substance | response to xenobiotic stimulus | cellular response to amino acid stimulus | mitotic cell cycle phase transition | establishment of blood-retinal barrier | cellular response to corticosteroid stimulus | cellular response to drug | response to bacterium | positive regulation of anion channel activity | cell communication | cellular response to mycotoxin | positive regulation of response to drug | response to quercetin | drug transmembrane transporter activity | positive regulation of transporter activity | cell cycle G2/M phase transition | positive regulation of transport | carbohydrate transport | cellular hyperosmotic response | positive regulation of molecular function | phospholipid transport | phosphatidylethanolamine-translocating ATPase activity | response to glucagon | cellular response to nutrient | ceramide-translocating ATPase activity | response to organic substance | gland development | response to glycoside | response to L-phenylalanine derivative | lactation | response to antineoplastic agent | cellular response to osmotic stress | xenobiotic transport | response to codeine | anatomical structure development | mitotic cell cycle | lipid localization | regulation of body fluid levels | amide transport | ceramide transporter activity | body fluid secretion | hormone transport | response to vitamin | animal organ development | positive regulation of ion transport | cellular response to salt stress | response to alkaloid | cellular response to steroid hormone stimulus | regulation of ion transmembrane transport | cellular response to dexamethasone stimulus | drug transport | hyperosmotic salinity response | cellular response to estradiol stimulus | maintenance of permeability of blood-brain barrier | transmembrane transport | response to organic cyclic compound | cell development | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | drug transmembrane transport | cation transport | response to biotic stimulus | ammonium transport | reproductive structure development | regulation of ion transport | developmental process | positive regulation of anion transport | phospholipid translocation | xenobiotic transmembrane transporting ATPase activity | response to thyroid hormone | digestion | regulation of transport | response to organonitrogen compound | cell cycle phase transition | regulation of anion transport | response to thyroxine | central nervous system development | response to anesthetic | lipid transporter activity | ion transport | antibiotic transport | placenta development | cellular response to organic substance | regulation of cell death | response to steroid hormone | negative regulation of cell death | daunorubicin transport | cellular response to L-glutamate | response to other organism | carbohydrate derivative transport | response to glucocorticoid | phospholipid-translocating ATPase activity | multicellular organismal process

GO Cellular Component

brush border | integral component of membrane | apical plasma membrane | cell projection membrane | cell | intrinsic component of membrane | intercellular canaliculus | brush border membrane | apical part of cell | cell-cell junction | cell projection | plasma membrane | cell periphery | cell surface | cell junction | membrane