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QuickView for ABCC1 (gene)


Gene Symbol:
ABCC1 Homo sapiens Homo sapiens
Full name:
ATP binding cassette subfamily C member 1
Synonyms:
ABC29, ABCC, GS-X, MRP, MRP1, multidrug resistance-associated protein 1, ATP-binding cassette transporter variant ABCC1delta-ex13, ATP-binding cassette transporter variant ABCC1delta-ex13&14, ATP-binding cassette transporter variant ABCC1delta-ex25, ATP-binding cassette transporter variant ABCC1delta-ex25&26, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, LTC4 transporter, leukotriene C(4) transporter
Genomic Location:
Chr 16: 15950935-16144432
Description:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily wh...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Danio rerio Schizosaccharomyces pombe Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 16
16p13.11





GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | anion transmembrane transporter activity | xenobiotic transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | sphingolipid transporter activity | nucleotide binding | ATPase-coupled anion transmembrane transporter activity | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | inorganic anion transmembrane transporter activity | catalytic activity | oligopeptide transmembrane transporter activity | ATP binding | tripeptide transmembrane transporter activity | phospholipid transporter activity | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | drug transmembrane transporter activity | glutathione S-conjugate-exporting ATPase activity | purine ribonucleoside triphosphate binding | peptide transmembrane transporter activity | hydrolase activity, acting on acid anhydrides | glutathione transmembrane transporter activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | sphingolipid-translocating ATPase activity | xenobiotic transmembrane transporting ATPase activity | cobalamin-transporting ATPase activity | vitamin transmembrane transporter activity | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | phospholipid-translocating ATPase activity

GO Biological Process

leukotriene metabolic process | cell motility | cobalamin metabolic process | lipid transport | ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | establishment of localization | oligopeptide transport | anion transmembrane transporter activity | response to drug | xenobiotic transmembrane transporter activity | glutathione transmembrane transport | membrane organization | cellular process | localization | anion transport | macromolecule localization | regulation of membrane lipid distribution | transmembrane transporter activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | sphingolipid transporter activity | cellular component organization | ATP hydrolysis coupled anion transmembrane transport | ATPase-coupled anion transmembrane transporter activity | response to stimulus | sphingolipid translocation | inorganic anion transport | cofactor metabolic process | oligopeptide transmembrane transport | inorganic anion transmembrane transporter activity | cell chemotaxis | oligopeptide transmembrane transporter activity | locomotion | nitrogen compound metabolic process | tripeptide transmembrane transporter activity | cell migration | phospholipid transporter activity | vitamin transport | ion transmembrane transport | organic substance transport | active transmembrane transporter activity | small molecule metabolic process | vitamin transmembrane transport | peptide transport | ion transmembrane transporter activity | glutathione transport | organic anion transport | tripeptide transport | drug transmembrane transporter activity | glutathione S-conjugate-exporting ATPase activity | drug metabolic process | carboxylic acid metabolic process | peptide transmembrane transporter activity | phospholipid transport | vitamin metabolic process | xenobiotic transport | anion transmembrane transport | cofactor transport | metabolic process | lipid localization | amide transport | organic substance metabolic process | drug transport | icosanoid metabolic process | cobalamin transport | transmembrane transport | glutathione transmembrane transporter activity | organic acid metabolic process | drug transmembrane transport | sphingolipid-translocating ATPase activity | phospholipid translocation | xenobiotic transmembrane transporting ATPase activity | heterocycle metabolic process | cobalamin-transporting ATPase activity | vitamin transmembrane transporter activity | lipid transporter activity | ion transport | cellular metabolic process | chemotaxis | phospholipid-translocating ATPase activity

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | plasma membrane | vacuole | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | basolateral plasma membrane | intracellular | membrane | vacuolar membrane