QuickView for ABCC3 (gene)

Gene Symbol:

ABCC3 Homo sapiens

Full name:

ATP binding cassette subfamily C member 3

Synonyms:

ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2, canalicular multispecific organic anion transporter 2, ATP-binding cassette sub-family C member 3, ATP-binding cassette, sub-family C (CFTR/MRP), member 3, canicular multispecific organic anion transporter, multi-specific organic anion transporter D, multidrug resistance associated protein, multidrug resistance-associated protein 3

Genomic Location:

Chr 17: 46067227-46124062

Description:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is i...

View Full Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTGGAGA_MIR5155P_MIR519E ,  GGGCGGR_SP1_Q6 ,  TTGCCAA_MIR182 ,  CTCCAAG_MIR432

Cytogenetic Map:

17q21.33

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