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QuickView for ABCC3 (gene)


Gene Symbol:
ABCC3 Homo sapiens Homo sapiens
Full name:
ATP binding cassette subfamily C member 3
Synonyms:
ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2, canalicular multispecific organic anion transporter 2, ATP-binding cassette sub-family C member 3, ATP-binding cassette, sub-family C (CFTR/MRP), member 3, canicular multispecific organic anion transporter, multi-specific organic anion transporter D, multidrug resistance associated protein, multidrug resistance-associated protein 3
Genomic Location:
Chr 17: 46067227-46124062
Description:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is i...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17
17q21.33





GO Molecular Function

bile acid transmembrane transporter activity | ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | anion transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | ATPase-coupled anion transmembrane transporter activity | hydrolase activity | carbohydrate derivative binding | organic acid transmembrane transporter activity | ATPase activity | pyrophosphatase activity | inorganic anion transmembrane transporter activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | bile acid-exporting ATPase activity | carboxylic acid transmembrane transporter activity | purine ribonucleoside triphosphate binding | hydrolase activity, acting on acid anhydrides | monocarboxylic acid transmembrane transporter activity | lipid-transporting ATPase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

bile acid transmembrane transporter activity | lipid transport | ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | secretion | monocarboxylic acid transport | localization | anion transport | macromolecule localization | transmembrane transporter activity | canalicular bile acid transport | ATP hydrolysis coupled anion transmembrane transport | ATPase-coupled anion transmembrane transporter activity | acid secretion | organic acid transmembrane transporter activity | inorganic anion transport | organic hydroxy compound transport | inorganic anion transmembrane transporter activity | carboxylic acid transmembrane transport | ion transmembrane transport | organic substance transport | active transmembrane transporter activity | organic acid transport | ion transmembrane transporter activity | organic anion transport | bile acid-exporting ATPase activity | carboxylic acid transmembrane transporter activity | anion transmembrane transport | organic acid transmembrane transport | lipid localization | bile acid and bile salt transport | monocarboxylic acid transmembrane transporter activity | lipid-transporting ATPase activity | transmembrane transport | carboxylic acid transport | lipid transporter activity | ion transport

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | plasma membrane | vacuole | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane | vacuolar membrane