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QuickView for ABCC4;jsessionid=D73CD364B55ED4A62B06B8E1E5623FF8;jsessionid=C2C1B82565C223CC56E35A8D1A76C3B1 (gene)


Gene Symbol:
Abcc4 Rattus norvegicus Rattus norvegicus
Full name:
ATP binding cassette subfamily C member 4
Synonyms:
Mrp4, RGD1565953, multidrug resistance-associated protein 4, ABC-tranporter, ATP-binding cassette protein C4, ATP-binding cassette, sub-family C (CFTR/MRP), member 4, ATP-binding cassette, subfamily C (CFTR/MRP), member 4
Genomic Location:
Chr 15: 103384848-103611238
Description:
ATP-binding cassette (ABC) multiple drug resistance protein (MRP) that mediates reduced glutatione release from hepatocytes into blood by cotransport with monoanionic bile salts
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_133411
XM_008770939
Protein Names
Q6QMG6



GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

positive regulation of smooth muscle cell proliferation | lipid transport | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | response to drug | cellular process | secretion | monocarboxylic acid transport | localization | anion transport | macromolecule localization | prostaglandin transport | regulation of cellular process | transmembrane transporter activity | cellular component organization | response to stimulus | acid secretion | regulation of cell proliferation | cellular component assembly | response to nitrogen compound | organelle assembly | fatty acid transport | prostaglandin secretion | organic substance transport | cell projection assembly | active transmembrane transporter activity | organic acid transport | organic anion transport | positive regulation of cell proliferation | response to organic substance | cell projection organization | lipid localization | cilium assembly | cilium organization | transmembrane transport | response to organic cyclic compound | carboxylic acid transport | organelle organization | response to organonitrogen compound | ion transport | regulation of smooth muscle cell proliferation

GO Cellular Component

secretory granule | integral component of membrane | organelle membrane | cytoplasmic vesicle | cell | platelet dense granule | intrinsic component of membrane | cytoplasm | intracellular organelle | secretory granule membrane | cell projection | secretory vesicle | endomembrane system | plasma membrane | cilium | vesicle | membrane-bounded organelle | platelet dense granule membrane | organelle | vesicle membrane | cell periphery | basolateral plasma membrane | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane