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QuickView for ABCG1 (gene)


Gene Symbol:
ABCG1 Homo sapiens Homo sapiens
Full name:
ATP binding cassette subfamily G member 1
Synonyms:
ABC8, WHITE1, ATP-binding cassette sub-family G member 1, ABC transporter 8, ATP-binding cassette transporter 8, ATP-binding cassette transporter member 1 of subfamily G, ATP-binding cassette, sub-family G (WHITE), member 1, homolog of Drosophila white, white protein homolog (ATP-binding cassette transporter 8)
Genomic Location:
Chr 21: 42492868-42590423
Description:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is i...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 21
21q22.3





GO Molecular Function

ADP binding | sterol-transporting ATPase activity | ATPase activity, coupled to transmembrane movement of substances | glycoprotein transporter activity | ribonucleotide binding | transmembrane transporter activity | lipid binding | toxin transmembrane transporter activity | sterol binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | phospholipid binding | ATPase activity | pyrophosphatase activity | cholesterol transporter activity | alcohol binding | catalytic activity | ATP binding | phospholipid transporter activity | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | identical protein binding | protein heterodimerization activity | sterol transporter activity | ion binding | organic cyclic compound binding | cholesterol binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | protein dimerization activity | hydrolase activity, acting on acid anhydrides | lipid-transporting ATPase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | steroid binding | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

detection of stimulus | extracellular structure organization | regulation of cholesterol transport | sterol-transporting ATPase activity | regulation of localization | lipid transport | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | response to hormone | negative regulation of cellular process | intracellular transport | regulation of lipid transport | sterol metabolic process | cellular process | localization | protein transport | positive regulation of cholesterol efflux | anion homeostasis | anion transport | macromolecule localization | intracellular cholesterol transport | glycoprotein transporter activity | negative regulation of cholesterol storage | establishment of localization in cell | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | transmembrane transporter activity | organic cyclic compound metabolic process | positive regulation of cholesterol biosynthetic process | cellular component organization | toxin transmembrane transporter activity | response to stimulus | regulation of macrophage derived foam cell differentiation | toxin transport | alcohol metabolic process | positive regulation of lipid biosynthetic process | regulation of plasma lipoprotein particle levels | sterol homeostasis | cholesterol homeostasis | cellular localization | organic hydroxy compound transport | regulation of cholesterol esterification | cholesterol transporter activity | regulation of steroid biosynthetic process | regulation of lipid storage | regulation of steroid metabolic process | regulation of nucleic acid-templated transcription | organic hydroxy compound metabolic process | nitrogen compound metabolic process | detection of chemical stimulus | phospholipid transporter activity | lipid metabolic process | regulation of cholesterol biosynthetic process | regulation of gene expression | organic substance transport | response to lipid | intracellular sterol transport | negative regulation of lipid storage | cellular response to high density lipoprotein particle stimulus | regulation of nitrogen compound metabolic process | active transmembrane transporter activity | small molecule metabolic process | peptide transport | regulation of cholesterol metabolic process | positive regulation of cholesterol transport | positive regulation of steroid metabolic process | sterol transporter activity | sterol transport | organic anion transport | cholesterol transport | positive regulation of lipid localization | cholesterol efflux | regulation of cellular metabolic process | amyloid precursor protein catabolic process | phospholipid homeostasis | homeostatic process | reverse cholesterol transport | plasma lipoprotein particle remodeling | regulation of RNA metabolic process | positive regulation of transport | regulation of lipid biosynthetic process | cellular response to lipoprotein particle stimulus | phospholipid transport | protein metabolic process | response to organic substance | positive regulation of steroid biosynthetic process | phospholipid efflux | metabolic process | lipid localization | regulation of RNA biosynthetic process | cholesterol metabolic process | high-density lipoprotein particle remodeling | amide transport | chemical homeostasis | organic substance metabolic process | ion homeostasis | establishment of protein localization | positive regulation of cholesterol metabolic process | lipid-transporting ATPase activity | steroid metabolic process | negative regulation of macrophage derived foam cell differentiation | transmembrane transport | regulation of transcription, DNA-templated | protein localization | regulation of developmental process | regulation of cholesterol efflux | low-density lipoprotein particle remodeling | glycoprotein transport | regulation of transport | protein-lipid complex remodeling | detection of hormone stimulus | regulation of lipid metabolic process | positive regulation of metabolic process | lipid transporter activity | positive regulation of lipid metabolic process | ion transport | positive regulation of lipid transport | lipid homeostasis | negative regulation of cell differentiation | carbohydrate derivative transport | amyloid precursor protein metabolic process | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | external side of plasma membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | nuclear outer membrane-endoplasmic reticulum membrane network | recycling endosome | endomembrane system | endoplasmic reticulum membrane | plasma membrane | vesicle | mitochondrion | Golgi membrane | endosome | membrane-bounded organelle | organelle | cell periphery | intracellular vesicle | cell surface | intracellular | membrane