Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for ABR;jsessionid=7F90671BF94EDD7742B2F6295F244611 (gene)


Gene Symbol:
ABR Homo sapiens Homo sapiens
Full name:
active BCR-related
Synonyms:
MDB, active breakpoint cluster region-related protein
Genomic Location:
Chr 17: 853509-1029881
Description:
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in ...
Orthologs:
Mus musculus Rattus norvegicus Pan troglodytes Canis lupus familiaris Bos taurus D. melanogaster
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
TGGAAA_NFAT_Q4_01 AACWWCAANK_UNKNOWN HNF4ALPHA_Q6 CACTGCC_MIR34A_MIR34C_MIR449 TTTGCAC_MIR19A_MIR19B MAZR_01 TCANNTGAY_SREBP1_01 RYTTCCTG_ETS2_B SRF_Q6 GCANCTGNY_MYOD_Q6
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 17
17p13.3





GO Molecular Function

Rho guanyl-nucleotide exchange factor activity | guanyl-nucleotide exchange factor activity | enzyme activator activity | GTPase binding | Rho GTPase binding | GTPase activator activity | enzyme binding | GTPase regulator activity | Ras GTPase binding | molecular function regulator | protein binding | Ras guanyl-nucleotide exchange factor activity | small GTPase binding | enzyme regulator activity

GO Biological Process

negative regulation of leukocyte activation | brain development | inner ear morphogenesis | Rho guanyl-nucleotide exchange factor activity | negative regulation of immune system process | actin filament-based process | guanyl-nucleotide exchange factor activity | positive regulation of cellular component organization | response to lipopolysaccharide | intracellular signal transduction | enzyme activator activity | positive regulation of apoptotic process | regulation of localization | regulation of programmed cell death | actin cytoskeleton organization | regulation of immune system process | negative regulation of cellular process | negative regulation of tissue remodeling | nervous system development | regulation of neutrophil degranulation | neuromuscular process controlling balance | positive regulation of GTPase activity | cellular process | negative regulation of inflammatory response | regulation of cell motility | GTPase activator activity | negative regulation of secretion | positive regulation of catalytic activity | negative regulation of cell migration | negative regulation of cell motility | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of blood vessel remodeling | regulation of cellular extravasation | small GTPase mediated signal transduction | cellular component organization | head development | response to stimulus | GTPase regulator activity | response to molecule of bacterial origin | negative regulation of transport | regulation of phagocytosis | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of neutrophil activation | embryo development | molecular function regulator | negative regulation of cellular extravasation | response to external biotic stimulus | system development | regulation of signal transduction | negative regulation of secretion by cell | multicellular organism development | regulation of catalytic activity | negative regulation of blood vessel remodeling | regulation of small GTPase mediated signal transduction | response to lipid | nervous system process | animal organ morphogenesis | regulation of cell migration | regulation of vascular permeability | regulation of cellular component movement | positive regulation of hydrolase activity | regulation of Rho protein signal transduction | negative regulation of immune response | regulation of GTPase activity | regulation of leukocyte migration | sensory organ development | response to bacterium | cell communication | negative regulation of cell activation | inner ear development | regulation of locomotion | positive regulation of transport | embryonic morphogenesis | positive regulation of molecular function | negative regulation of exocytosis | embryonic organ morphogenesis | response to organic substance | regulation of intracellular signal transduction | regulation of exocytosis | anatomical structure development | negative regulation of neutrophil degranulation | embryonic organ development | ear development | regulation of tissue remodeling | regulation of vesicle-mediated transport | Ras guanyl-nucleotide exchange factor activity | regulation of secretion | positive regulation of cell death | animal organ development | regulation of cell activation | negative regulation of cellular component movement | positive regulation of programmed cell death | positive regulation of phagocytosis | cytoskeleton organization | regulation of regulated secretory pathway | regulation of cell communication | signaling | neuromuscular process | regulation of endocytosis | enzyme regulator activity | regulation of Ras protein signal transduction | anatomical structure morphogenesis | response to biotic stimulus | negative regulation of leukocyte migration | regulation of developmental process | developmental process | organelle organization | regulation of transport | central nervous system development | regulation of cell death | regulation of inflammatory response | ear morphogenesis | negative regulation of locomotion | positive regulation of endocytosis | regulation of cellular component organization | response to other organism | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

cell | cytoplasm | plasma membrane | cell periphery | cytosol | intracellular | membrane