QuickView for ACTA2 (gene)

Gene Symbol:

ACTA2 Homo sapiens

Full name:

actin, alpha 2, smooth muscle, aorta

Synonyms:

ACTSA, actin, aortic smooth muscle, alpha-cardiac actin, cell growth-inhibiting gene 46 protein

Genomic Location:

Chr 10: 90684811-90702491

Description:

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular ...

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This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

miRNA binding sites
(Source: miRecords):

hsa-miR-21 Targeted Genes

Cytogenetic Map:

10q23.31

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