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QuickView for ACTA2 (gene)

Gene Symbol:
ACTA2 Homo sapiens Homo sapiens
Full name:
actin, alpha 2, smooth muscle, aorta
ACTSA, actin, aortic smooth muscle, alpha-cardiac actin, cell growth-inhibiting gene 46 protein
Genomic Location:
Chr 10: 90684811-90702491
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular ...
Mus musculus Rattus norvegicus D. melanogaster Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 10

Transcripts Names
Protein Names

GO Molecular Function

kinase binding | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of blood vessel diameter | positive regulation of macromolecule biosynthetic process | response to virus | vascular smooth muscle contraction | mesangial cell development | glomerular mesangial cell development | cell differentiation | glomerulus development | mesenchyme development | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cellular process | regulation of metabolic process | epithelium development | smooth muscle contraction | urogenital system development | muscle contraction | response to stimulus | vasculature development | pericyte cell differentiation | regulation of blood vessel size | epithelial cell development | cardiovascular system development | blood circulation | positive regulation of RNA biosynthetic process | kidney development | blood vessel development | negative regulation of blood vessel diameter | regulation of nucleic acid-templated transcription | mesenchyme migration | response to external biotic stimulus | system development | multicellular organism development | glomerulus vasculature development | regulation of gene expression | regulation of blood pressure | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | cell differentiation involved in kidney development | vasoconstriction | mesenchyme morphogenesis | regulation of cellular metabolic process | regulation of RNA metabolic process | renal system development | regulation of tube size | nephron development | tissue morphogenesis | anatomical structure development | regulation of RNA biosynthetic process | regulation of tube diameter | connective tissue development | animal organ development | regulation of transcription, DNA-templated | cell development | anatomical structure morphogenesis | response to biotic stimulus | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | epithelial cell differentiation | positive regulation of metabolic process | circulatory system development | muscle system process | response to other organism | positive regulation of gene expression | multicellular organismal process

GO Cellular Component

supramolecular fiber | cell body | actin-based cell projection | cell | smooth muscle contractile fiber | lamellipodium | cytoplasm | intracellular organelle | actin cytoskeleton | contractile fiber | protein-containing complex | cell projection | cell leading edge | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | filopodium | organelle | extracellular space | cytosol | cytoskeleton | intracellular | supramolecular complex