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QuickView for ADA;jsessionid=43ABB93FFF8183C403C970D709A97FBB;jsessionid=CF3711F254F213984F898B70F4288FE0 (gene)


Gene Symbol:
Ada Mus musculus Mus musculus
Full name:
adenosine deaminase
Synonyms:
adenosine deaminase, adenosine aminohydrolase
Genomic Location:
Chr 2: 163552320-163575913
Orthologs:
Homo sapiens Rattus norvegicus C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Bos taurus Gallus gallus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_007398
NM_001272052
Protein Names
Q4FK28
P03958



GO Molecular Function

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | cation binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | ion binding | deaminase activity | organic cyclic compound binding | purine nucleoside binding | zinc ion binding | adenosine deaminase activity | transition metal ion binding | nucleoside binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

positive regulation of immune response | positive regulation of heart contraction | response to extracellular stimulus | negative regulation of G-protein coupled receptor protein signaling pathway | xanthine biosynthetic process | regulation of muscle system process | purine ribonucleoside monophosphate biosynthetic process | blastocyst formation | response to nutrient levels | negative regulation of immune system process | positive regulation of blood circulation | mucosal-associated lymphoid tissue development | regulation of B cell activation | nucleoside phosphate catabolic process | developmental process involved in reproduction | regulation of localization | response to isoquinoline alkaloid | regulation of programmed cell death | establishment of localization | regulation of immune system process | negative regulation of mature B cell apoptotic process | negative regulation of cellular process | hypoxanthine biosynthetic process | positive regulation of developmental process | positive regulation of lymphocyte activation | cell differentiation | regulation of T cell differentiation | respiratory tube development | deoxyribonucleoside triphosphate metabolic process | regulation of smooth muscle contraction | response to drug | organophosphate catabolic process | positive regulation of cell adhesion | nucleoside catabolic process | B cell differentiation | positive regulation of T cell differentiation | regulation of circadian sleep/wake cycle | histamine secretion | cellular process | positive regulation of T cell differentiation in thymus | secretion | organic substance catabolic process | response to morphine | negative regulation of inflammatory response | lymphocyte differentiation | regulation of cell motility | localization | regulation of calcium-mediated signaling | nucleotide metabolic process | negative regulation of signaling | reproductive system development | positive regulation of adaptive immune response | carbohydrate derivative catabolic process | immune system development | azole transport | purine nucleotide biosynthetic process | negative regulation of apoptotic process | negative regulation of secretion | response to hypoxia | nucleoside triphosphate metabolic process | germinal center B cell differentiation | negative regulation of cell migration | purine nucleoside catabolic process | deoxyribonucleoside catabolic process | regulation of T cell receptor signaling pathway | regulation of behavior | tissue development | regulation of cell differentiation | histamine transport | regulation of lymphocyte apoptotic process | adenosine metabolic process | negative regulation of cell motility | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of apoptotic process | catabolic process | hepaticobiliary system development | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | T cell activation | response to stimulus | positive regulation of antigen receptor-mediated signaling pathway | purine nucleotide metabolic process | negative regulation of T cell apoptotic process | respiratory system development | hypoxanthine salvage | positive regulation of immune system process | response to stress | negative regulation of circadian rhythm | leukocyte activation involved in immune response | positive regulation of lymphocyte proliferation | mature B cell differentiation | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | regulation of blood circulation | positive regulation of cell-cell adhesion | positive regulation of B cell proliferation | purine nucleobase biosynthetic process | negative regulation of mucus secretion | positive regulation of cell activation | regulation of heart rate | reproduction | cellular nitrogen compound metabolic process | purine nucleotide salvage | positive regulation of T cell activation | negative regulation of transport | carbohydrate derivative biosynthetic process | hemopoiesis | regulation of circadian sleep/wake cycle, non-REM sleep | regulation of mucus secretion | deoxyribose phosphate catabolic process | regulation of cell adhesion | cellular biosynthetic process | purine nucleoside metabolic process | embryo development | nucleobase-containing compound catabolic process | drug catabolic process | nucleotide biosynthetic process | regulation of lymphocyte differentiation | leukocyte differentiation | response to nitrogen compound | lung alveolus development | negative regulation of adenosine receptor signaling pathway | positive regulation of mononuclear cell proliferation | system development | response to oxygen levels | regulation of penile erection | nitrogen compound metabolic process | purine deoxyribonucleoside triphosphate catabolic process | reproductive process | regulation of signal transduction | multicellular organism development | positive regulation of lymphocyte differentiation | phosphorus metabolic process | ribonucleoside monophosphate biosynthetic process | purine ribonucleoside catabolic process | response to vitamin E | regulation of muscle contraction | embryonic digestive tract development | trophectodermal cell differentiation | regulation of T cell activation | positive regulation of alpha-beta T cell differentiation | organic substance transport | organophosphate metabolic process | nucleoside metabolic process | regulation of lymphocyte activation | deoxyribonucleotide metabolic process | nucleobase-containing small molecule catabolic process | response to ammonium ion | purine deoxyribonucleoside metabolic process | liver development | negative regulation of lymphocyte apoptotic process | regulation of germinal center formation | pigment biosynthetic process | regulation of cell migration | negative regulation of circadian sleep/wake cycle, non-REM sleep | small molecule metabolic process | positive regulation of intracellular signal transduction | regulation of cellular component movement | inosine biosynthetic process | response to nutrient | positive regulation of cell differentiation | nucleobase-containing small molecule metabolic process | mature B cell differentiation involved in immune response | positive regulation of calcium-mediated signaling | B cell activation | biosynthetic process | negative regulation of B cell apoptotic process | aromatic compound biosynthetic process | regulation of cell adhesion mediated by integrin | digestive tract development | nucleotide catabolic process | response to xenobiotic stimulus | regulation of circadian sleep/wake cycle, sleep | regulation of heart contraction | regulation of leukocyte migration | phosphate-containing compound metabolic process | regulation of B cell apoptotic process | chordate embryonic development | deoxyadenosine catabolic process | positive regulation of smooth muscle contraction | regulation of alpha-beta T cell differentiation | regulation of T cell apoptotic process | cell activation involved in immune response | positive regulation of signal transduction | aromatic compound catabolic process | positive regulation of cell proliferation | regulation of locomotion | embryo development ending in birth or egg hatching | positive regulation of B cell activation | regulation of cell-cell adhesion mediated by integrin | drug metabolic process | lymphocyte activation | negative regulation of thymocyte apoptotic process | deoxyribonucleoside triphosphate catabolic process | positive regulation of heart rate | response to organic substance | gland development | negative regulation of behavior | digestive system development | regulation of hemopoiesis | regulation of intracellular signal transduction | anatomical structure development | metabolic process | positive regulation of T cell receptor signaling pathway | regulation of adaptive immune response | regulation of thymocyte apoptotic process | positive regulation of leukocyte activation | regulation of body fluid levels | negative regulation of programmed cell death | embryonic organ development | regulation of secretion | cell adhesion | immune response | nucleobase-containing compound metabolic process | positive regulation of muscle contraction | organic substance metabolic process | response to vitamin | pigment metabolic process | animal organ development | regulation of cell activation | negative regulation of cellular component movement | hypoxanthine metabolic process | dATP catabolic process | negative regulation of circadian sleep/wake cycle, sleep | response to alkaloid | blastocyst development | purine-containing compound salvage | cell activation | lung development | anatomical structure formation involved in morphogenesis | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of signal transduction | response to organic cyclic compound | dATP metabolic process | nucleoside triphosphate catabolic process | negative regulation of leukocyte apoptotic process | regulation of T cell differentiation in thymus | B cell activation involved in immune response | anatomical structure morphogenesis | cation transport | Peyer's patch development | ammonium transport | regulation of circadian rhythm | reproductive structure development | negative regulation of leukocyte migration | regulation of developmental process | regulation of G-protein coupled receptor protein signaling pathway | developmental process | positive regulation of alpha-beta T cell activation | purine nucleobase metabolic process | tube development | carbohydrate derivative metabolic process | regulation of transport | deoxyribonucleotide catabolic process | regulation of B cell proliferation | regulation of cell-cell adhesion | neurotransmitter transport | response to organonitrogen compound | heterocycle metabolic process | positive regulation of germinal center formation | response to anesthetic | in utero embryonic development | ion transport | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | placenta development | negative regulation of penile erection | regulation of cell death | negative regulation of cell death | regulation of inflammatory response | adenosine catabolic process | negative regulation of locomotion | positive regulation of leukocyte cell-cell adhesion | positive regulation of signaling | nucleoside monophosphate biosynthetic process | regulation of signaling | purine nucleotide catabolic process | multicellular organismal process

GO Cellular Component

dendrite | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | neuronal cell body | external side of plasma membrane | cytoplasm | dendrite cytoplasm | intracellular organelle | dendritic tree | cell projection | plasma membrane bounded cell projection cytoplasm | plasma membrane | vacuole | vesicle | cytoplasmic region | lytic vacuole | extracellular region | membrane-bounded organelle | organelle | lysosome | extracellular space | cell periphery | cytosol | intracellular vesicle | cell surface | intracellular | cell junction | membrane