QuickView for ADAM10 (gene)

Gene Symbol:

ADAM10 Homo sapiens

Full name:

ADAM metallopeptidase domain 10

Synonyms:

AD10, AD18, CD156c, CDw156, HsT18717, MADM, RAK, kuz, disintegrin and metalloproteinase domain-containing protein 10, a disintegrin and metalloprotease domain 10, kuzbanian protein homolog, mammalian disintegrin-metalloprotease

Genomic Location:

Chr 15: 56675802-56829469

Description:

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar ...

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Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CGTSACG_PAX3_B ,  SP1_01 ,  GTATTAT_MIR3693P ,  MCAATNNNNNGCG_UNKNOWN ,  USF_Q6 ,  RYTTCCTG_ETS2_B ,  CACGTG_MYC_Q2 ,  ATGTACA_MIR493 ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  CTTTGTA_MIR524 ,  TATAAA_TATA_01 ,  CDPCR3HD_01 ,  TFIII_Q6 ,  GTGACGY_E4F1_Q6 ,  CAGGTG_E12_Q6 ,  CAGCTTT_MIR320 ,  CDPCR1_01 ,  AGTCTTA_MIR499 ,  GGGCGGR_SP1_Q6 ,  ATGTTTC_MIR494 ,  USF_01 ,  NRF1_Q6 ,  NMYC_01 ,  TTGCCAA_MIR182 ,  USF_Q6_01 ,  ATATGCA_MIR448 ,  GTTATAT_MIR410 ,  GGTAACC_MIR4095P ,  RCGCANGCGY_NRF1_Q6 ,  TATTATA_MIR374 ,  SP1_Q2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-122a ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-346 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-494 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-499

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Cytogenetic Map:

15q21.3

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