QuickView for ADAMTS7;jsessionid=21643CEDDB7FA12B74FDAA039FECE313 (gene)

Gene Symbol:

ADAMTS7 Homo sapiens

Full name:

ADAM metallopeptidase with thrombospondin type 1 motif 7

Synonyms:

ADAM-TS 7, ADAM-TS7, ADAMTS-7, A disintegrin and metalloproteinase with thrombospondin motifs 7, COMPase, a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7

Genomic Location:

Chr 15: 76838600-76890828

Description:

The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this fa...

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The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  TGGNNNNNNKCCAR_UNKNOWN ,  SP3_Q3

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-29

Cytogenetic Map:

15q25.1

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