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QuickView for ADCY2;jsessionid=E67AC4A221E7BD3706243AB3FA8CCE97 (gene)


Gene Symbol:
ADCY2 Homo sapiens Homo sapiens
Full name:
adenylate cyclase 2
Synonyms:
AC2, HBAC2, adenylate cyclase type 2, 3',5'-cyclic AMP synthetase, ATP pyrophosphate-lyase 2, adenylate cyclase 2 (brain), adenylate cyclase II, adenylate cyclase type II, adenylyl cyclase 2, type II adenylate cyclase
Genomic Location:
Chr 5: 7449343-7883194
Description:
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 5
5p15.31





GO Molecular Function

cation binding | adenylate cyclase binding | magnesium ion binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | lyase activity | adenylate cyclase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | protein heterodimerization activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | manganese ion binding | protein dimerization activity | transition metal ion binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | phosphorus-oxygen lyase activity | metal ion binding | heterocyclic compound binding | small molecule binding | cyclase activity

GO Biological Process

purine ribonucleotide metabolic process | cyclic nucleotide biosynthetic process | intracellular signal transduction | response to hormone | response to drug | renal water homeostasis | response to antibiotic | cellular process | nucleotide metabolic process | cAMP biosynthetic process | ribose phosphate metabolic process | purine nucleotide biosynthetic process | ribonucleotide metabolic process | response to peptide hormone | regulation of cellular process | cellular response to lipid | organic cyclic compound metabolic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | response to stimulus | purine nucleotide metabolic process | cellular nitrogen compound biosynthetic process | cyclic purine nucleotide metabolic process | multicellular organismal homeostasis | response to peptide | response to alcohol | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | carbohydrate derivative biosynthetic process | G-protein coupled receptor signaling pathway | cellular biosynthetic process | nucleotide biosynthetic process | cellular response to forskolin | water homeostasis | response to nitrogen compound | cellular response to hormone stimulus | nitrogen compound metabolic process | cellular response to antibiotic | cellular response to peptide hormone stimulus | phosphorus metabolic process | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | cyclic nucleotide metabolic process | response to ketone | response to lipid | cellular response to peptide | organophosphate metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | second-messenger-mediated signaling | biosynthetic process | aromatic compound biosynthetic process | purine ribonucleotide biosynthetic process | phosphate-containing compound metabolic process | cellular response to drug | cell communication | cyclic-nucleotide-mediated signaling | homeostatic process | cAMP metabolic process | response to glucagon | response to organic substance | cAMP-mediated signaling | metabolic process | regulation of body fluid levels | chemical homeostasis | nucleobase-containing compound metabolic process | organic substance metabolic process | renal system process | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | signaling | response to organic cyclic compound | ribose phosphate biosynthetic process | carbohydrate derivative metabolic process | multicellular organismal water homeostasis | response to organonitrogen compound | heterocycle metabolic process | cellular metabolic process | cellular response to organic substance | cellular response to glucagon stimulus | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | neuron projection | somatodendritic compartment | cell | intrinsic component of membrane | cytoplasm | membrane microdomain | dendritic tree | cell projection | plasma membrane | membrane raft | integral component of plasma membrane | cell periphery | intracellular | membrane | intrinsic component of plasma membrane