QuickView for ADGRE2;jsessionid=BB53768A64D1432CCD5F785C7D4426C5 (gene)

Gene Symbol:

ADGRE2 Homo sapiens

Full name:

adhesion G protein-coupled receptor E2

Synonyms:

CD312, EMR2, VBU, adhesion G protein-coupled receptor E2, EGF-like module-containing mucin-like hormone receptor-like 2, egf-like module containing, mucin-like, hormone receptor-like 2

Genomic Location:

Chr 19: 14704205-14750353

Description:

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mai...

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This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Orthologs:

Macaca mulatta ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Cytogenetic Map:

19p13.12

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