QuickView for ADH7 (gene)

Gene Symbol:

ADH7 Homo sapiens

Full name:

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Synonyms:

ADH4, alcohol dehydrogenase class 4 mu/sigma chain, alcohol dehydrogenase VII, alcohol dehydrogenase class IV mu/sigma chain, alcohol dehydrogenase-7, class IV sigma-1 alcohol dehydrogenase, class IV sigmasigma alcohol dehydrogenase, gastric alcohol dehydrogenase, retinol dehydrogenase

Genomic Location:

Chr 4: 100552441-100575548

Description:

This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethan...

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This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CEBP_Q2_01

Cytogenetic Map:

4q23

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