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QuickView for ADORA1;jsessionid=2111B80A389BE5054565A651D218425B;jsessionid=B760222D4FDD1FA4C24475090DCA5D59 (gene)


Gene Symbol:
Adora1 Rattus norvegicus Rattus norvegicus
Full name:
adenosine A1 receptor
Synonyms:
adenosine receptor A1
Genomic Location:
Chr 13: 47159042-47193163
Description:
inhibits adenylyl cyclase activity; plays a role in regulation of arterial pressure, heart rate, and sodium excretion
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: miRecords):


Transcripts Names
NM_017155
XM_006249861
XM_006249859
Protein Names
P25099



GO Molecular Function

heterotrimeric G-protein binding | transmembrane signaling receptor activity | protein-containing complex binding | G-protein coupled receptor activity | signaling receptor binding | G-protein beta/gamma-subunit complex binding | carbohydrate derivative binding | signaling receptor activity | protein heterodimerization activity | organic cyclic compound binding | purine nucleoside binding | protein binding | protein dimerization activity | G-protein coupled receptor binding | nucleoside binding | heat shock protein binding | heterocyclic compound binding | G-protein coupled adenosine receptor activity | small molecule binding

GO Biological Process

regulation of blood vessel diameter | regulation of muscle system process | regulation of dephosphorylation | negative regulation of immune system process | detection of stimulus | negative regulation of muscle contraction | regulation of localization | regulation of programmed cell death | positive regulation of lipid catabolic process | positive regulation of peptidyl-tyrosine phosphorylation | establishment of localization | regulation of immune system process | negative regulation of cellular process | regulation of MAP kinase activity | excitatory postsynaptic potential | positive regulation of signaling receptor activity | positive regulation of nucleoside transport | regulation of smooth muscle contraction | positive regulation of phosphate metabolic process | regulation of renal sodium excretion | intracellular transport | regulation of circadian sleep/wake cycle | regulation of neuron death | positive regulation of dephosphorylation | cellular process | organic substance catabolic process | negative regulation of inflammatory response | positive regulation of epidermal growth factor-activated receptor activity | regulation of cell motility | localization | positive regulation of synaptic transmission | regulation of respiratory gaseous exchange | protein transport | negative regulation of glutamate secretion | negative regulation of signaling | chemical synaptic transmission | anion homeostasis | positive regulation of protein kinase activity | negative regulation of amino acid transport | macromolecule localization | negative regulation of apoptotic process | negative regulation of secretion | response to hypoxia | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | negative regulation of hormone secretion | establishment of localization in cell | regulation of behavior | regulation of neurological system process | negative regulation of cell motility | negative regulation of acute inflammatory response | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | positive regulation of cellular protein metabolic process | positive regulation of potassium ion transport | regulation of respiratory gaseous exchange by neurological system process | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | G-protein coupled receptor activity | regulation of peptide secretion | response to stimulus | positive regulation of blood pressure | regulation of long-term synaptic potentiation | regulation of peptidyl-tyrosine phosphorylation | regulation of excretion | positive regulation of protein metabolic process | regulation of blood vessel size | response to stress | intracellular protein transport | negative regulation of circadian rhythm | regulation of cell proliferation | multicellular organismal homeostasis | regulation of blood circulation | regulation of cardiac muscle cell contraction | sensory perception of temperature stimulus | negative regulation of mucus secretion | cellular localization | response to temperature stimulus | negative regulation of transport | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | regulation of circadian sleep/wake cycle, non-REM sleep | regulation of mucus secretion | regulation of peptide transport | modulation of chemical synaptic transmission | cell-cell signaling | positive regulation of protein dephosphorylation | activation of protein kinase activity | positive regulation of ERBB signaling pathway | cell surface receptor signaling pathway involved in cell-cell signaling | negative regulation of blood pressure | detection of temperature stimulus involved in sensory perception | negative regulation of blood vessel diameter | positive regulation of peptide secretion | regulation of membrane potential | detection of abiotic stimulus | regulation of protein tyrosine kinase activity | response to oxygen levels | regulation of signal transduction | negative regulation of secretion by cell | regulation of synaptic transmission, GABAergic | regulation of synaptic transmission, glutamatergic | regulation of MAPK cascade | negative regulation of lipid catabolic process | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | relaxation of muscle | regulation of muscle contraction | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | regulation of hormone levels | regulation of sensory perception of pain | regulation of hormone secretion | regulation of acute inflammatory response | regulation of postsynaptic membrane potential | protein localization to membrane | positive regulation of secretion | organic substance transport | nervous system process | regulation of blood pressure | synaptic signaling | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | negative regulation of circadian sleep/wake cycle, non-REM sleep | peptide transport | positive regulation of intracellular signal transduction | regulation of cellular component movement | cognition | regulation of glomerular filtration | sensory perception of pain | regulation of cellular protein metabolic process | negative regulation of ion transport | triglyceride homeostasis | positive regulation of neuron death | regulation of glutamate secretion | detection of temperature stimulus involved in sensory perception of pain | regulation of circadian sleep/wake cycle, sleep | regulation of heart contraction | negative regulation of synaptic transmission, glutamatergic | regulation of leukocyte migration | regulation of striated muscle contraction | regulation of long term synaptic depression | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of lipid catabolic process | regulation of respiratory system process | activation of MAPKK activity | regulation of cardiac muscle contraction | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | regulation of protein phosphorylation | regulation of locomotion | negative regulation of synaptic transmission, GABAergic | regulation of tube size | positive regulation of transport | positive regulation of systemic arterial blood pressure | regulation of potassium ion transport | positive regulation of molecular function | establishment of protein localization to membrane | regulation of signaling receptor activity | regulation of epidermal growth factor-activated receptor activity | positive regulation of protein modification process | negative regulation of behavior | regulation of protein dephosphorylation | regulation of kinase activity | response to mechanical stimulus | fatty acid homeostasis | detection of stimulus involved in sensory perception | regulation of intracellular signal transduction | cell surface receptor signaling pathway | vasodilation | negative regulation of lipid metabolic process | metabolic process | negative regulation of long-term synaptic potentiation | relaxation of vascular smooth muscle | regulation of body fluid levels | negative regulation of programmed cell death | regulation of tube diameter | cellular protein localization | amide transport | negative regulation of heart contraction | chemical homeostasis | regulation of secretion | positive regulation of cell death | relaxation of smooth muscle | lipid catabolic process | organic substance metabolic process | regulation of epidermal growth factor receptor signaling pathway | adenosine receptor signaling pathway | positive regulation of ion transport | negative regulation of cellular component movement | positive regulation of kinase activity | negative regulation of circadian sleep/wake cycle, sleep | ion homeostasis | regulation of phosphate metabolic process | renal system process | establishment of protein localization | negative regulation of long term synaptic depression | positive regulation of MAPK cascade | temperature homeostasis | sensory perception | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | negative regulation of systemic arterial blood pressure | regulation of ERBB signaling pathway | protein localization | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | positive regulation of epidermal growth factor receptor signaling pathway | cellular macromolecule localization | positive regulation of MAP kinase activity | regulation of circadian rhythm | negative regulation of leukocyte migration | regulation of ion transport | protein targeting to membrane | renal system process involved in regulation of systemic arterial blood pressure | detection of temperature stimulus | acylglycerol homeostasis | regulation of transport | negative regulation of cell proliferation | negative regulation of smooth muscle contraction | negative regulation of synaptic transmission | regulation of anion transport | regulation of lipid metabolic process | positive regulation of metabolic process | regulation of actin filament-based process | regulation of synaptic plasticity | protein targeting | positive regulation of lipid metabolic process | G-protein coupled adenosine receptor activity | negative regulation of renal sodium excretion | regulation of cell death | negative regulation of cell death | positive regulation of blood vessel diameter | regulation of inflammatory response | negative regulation of neurotrophin production | negative regulation of locomotion | lipid homeostasis | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | response to auditory stimulus | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

presynaptic membrane | dendritic spine | integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | axolemma | somatodendritic compartment | integral component of presynaptic membrane | cell projection membrane | cell body | cell | neuronal cell body | distal axon | intrinsic component of membrane | synaptic membrane | terminal bouton | cytoplasm | intracellular organelle | endoplasmic reticulum | dendritic tree | leading edge membrane | main axon | presynapse | cell projection | postsynaptic membrane | endomembrane system | neuron spine | postsynapse | plasma membrane | cell leading edge | postsynaptic density | asymmetric synapse | integral component of postsynaptic membrane | integral component of plasma membrane | membrane-bounded organelle | organelle | postsynaptic specialization | axon terminus | presynaptic active zone | cell periphery | axon | basolateral plasma membrane | neuron projection terminus | intracellular | membrane | neuron projection membrane | intrinsic component of plasma membrane