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QuickView for ADORA2B;jsessionid=97514A4378D275C892A1BC8FA33AF014 (gene)


Gene Symbol:
ADORA2B Homo sapiens Homo sapiens
Full name:
adenosine A2b receptor
Synonyms:
ADORA2, adenosine receptor A2b
Genomic Location:
Chr 17: 15788956-15819935
Description:
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chro...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 17
17p12





GO Molecular Function

transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor activity | G-protein coupled adenosine receptor activity

GO Biological Process

positive regulation of immune response | positive regulation of cyclase activity | response to extracellular stimulus | regulation of blood vessel diameter | regulation of muscle system process | regulation of cellular localization | positive regulation of lyase activity | intracellular signal transduction | negative regulation of muscle contraction | regulation of localization | regulation of immune system process | regulation of MAP kinase activity | defense response | cellular response to extracellular stimulus | regulation of smooth muscle contraction | positive regulation of phosphate metabolic process | positive regulation of cellular biosynthetic process | cellular process | positive regulation of immune effector process | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of immune response | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | regulation of mast cell degranulation | MAPK cascade | G-protein coupled receptor activity | response to stimulus | JNK cascade | positive regulation of immune system process | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | regulation of blood vessel size | response to stress | positive regulation of mast cell degranulation | positive regulation of cell activation | positive regulation of vascular endothelial growth factor production | regulation of guanylate cyclase activity | blood circulation | G-protein coupled receptor signaling pathway | positive regulation of protein serine/threonine kinase activity | protein modification process | macromolecule modification | activation of protein kinase activity | regulation of intracellular transport | stress-activated protein kinase signaling cascade | positive regulation of exocytosis | positive regulation of guanylate cyclase activity | nitrogen compound metabolic process | regulation of signal transduction | regulation of MAPK cascade | phosphorus metabolic process | positive regulation of inflammatory response | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | relaxation of muscle | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of muscle contraction | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of cGMP-mediated signaling | positive regulation of secretion | cellular response to stress | excretion | positive regulation of chronic inflammatory response to non-antigenic stimulus | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of mast cell activation | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | second-messenger-mediated signaling | stress-activated MAPK cascade | regulation of cellular protein metabolic process | phosphorylation | positive regulation of chemokine production | regulation of cyclase activity | protein phosphorylation | phosphate-containing compound metabolic process | positive regulation of regulated secretory pathway | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | cyclic-nucleotide-mediated signaling | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | regulation of tube size | positive regulation of transport | positive regulation of molecular function | activation of MAPK activity | activation of adenylate cyclase activity | protein metabolic process | positive regulation of protein modification process | cAMP-mediated signaling | regulation of kinase activity | regulation of intracellular signal transduction | regulation of exocytosis | cell surface receptor signaling pathway | vasodilation | regulation of chronic inflammatory response | metabolic process | positive regulation of cGMP-mediated signaling | positive regulation of leukocyte activation | relaxation of vascular smooth muscle | regulation of tube diameter | regulation of vesicle-mediated transport | regulation of secretion | positive regulation of interleukin-6 production | relaxation of smooth muscle | positive regulation of mast cell activation | organic substance metabolic process | adenosine receptor signaling pathway | regulation of cell activation | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of cytokine production | regulation of regulated secretory pathway | positive regulation of intracellular transport | positive regulation of MAPK cascade | positive regulation of chronic inflammatory response | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | positive regulation of MAP kinase activity | cellular protein modification process | regulation of chemokine production | regulation of transport | cellular defense response | regulation of vascular endothelial growth factor production | negative regulation of smooth muscle contraction | positive regulation of metabolic process | G-protein coupled adenosine receptor activity | cellular metabolic process | regulation of interleukin-6 production | positive regulation of blood vessel diameter | regulation of inflammatory response | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | intracellular | membrane | intrinsic component of plasma membrane