QuickView for ADRB1 (gene)

Gene Symbol:

ADRB1 Homo sapiens

Full name:

adrenoceptor beta 1

Synonyms:

ADRB1R, B1AR, BETA1AR, RHR, beta-1 adrenergic receptor, adrenergic, beta-1-, receptor, beta-1 adrenoceptor, beta-1 adrenoreceptor

Genomic Location:

Chr 10: 115793796-115796657

Description:

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart...

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The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  RTAAACA_FREAC2_01 ,  VDR_Q3 ,  GCANCTGNY_MYOD_Q6 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  GGGYGTGNY_UNKNOWN ,  CAGGTG_E12_Q6 ,  AP2_Q6_01 ,  GGGCGGR_SP1_Q6 ,  CCCNNGGGAR_OLF1_01 ,  SPZ1_01 ,  WTTGKCTG_UNKNOWN ,  FREAC4_01 ,  SP1_Q2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-30

Cytogenetic Map:

10q25.3

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