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QuickView for ADRB3 (gene)


Gene Symbol:
ADRB3 Homo sapiens Homo sapiens
Full name:
adrenoceptor beta 3
Synonyms:
BETA3AR, beta-3 adrenergic receptor, adrenergic, beta-3-, receptor, beta-3 adrenoceptor, beta-3 adrenoreceptor
Genomic Location:
Chr 8: 37939673-37943341
Description:
The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Canis lupus familiaris Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 8
8p11.23


Transcripts Names
NM_000025
Protein Names
P13945
Q4JFT4
A8KAG8



GO Molecular Function

beta-3 adrenergic receptor binding | epinephrine binding | beta3-adrenergic receptor activity | transmembrane signaling receptor activity | beta-adrenergic receptor activity | G-protein coupled receptor activity | signaling receptor binding | G-protein coupled amine receptor activity | adrenergic receptor binding | adrenergic receptor activity | signaling receptor activity | identical protein binding | organic cyclic compound binding | protein binding | protein homodimerization activity | protein dimerization activity | G-protein coupled receptor binding | norepinephrine binding

GO Biological Process

response to extracellular stimulus | negative regulation of G-protein coupled receptor protein signaling pathway | regulation of blood vessel diameter | response to nutrient levels | intracellular signal transduction | establishment of localization | negative regulation of cellular process | cell differentiation | regulation of systemic arterial blood pressure by norepinephrine-epinephrine | generation of precursor metabolites and energy | positive regulation of phosphate metabolic process | response to antibiotic | adaptive thermogenesis | cellular process | localization | negative regulation of signaling | beta3-adrenergic receptor activity | negative regulation of developmental growth | diet induced thermogenesis | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | brown fat cell differentiation | regulation of binding | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | regulation of systemic arterial blood pressure mediated by a chemical signal | beta-adrenergic receptor activity | G-protein coupled receptor activity | response to stimulus | positive regulation of cold-induced thermogenesis | positive regulation of protein metabolic process | regulation of blood vessel size | response to cold | response to stress | adenylate cyclase-activating adrenergic receptor signaling pathway | multicellular organismal homeostasis | G-protein coupled amine receptor activity | response to temperature stimulus | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of blood pressure | adrenergic receptor activity | regulation of signal transduction | negative regulation of growth | regulation of MAPK cascade | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of catalytic activity | regulation of phosphorylation | regulation of blood pressure | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | vesicle-mediated transport | fat cell differentiation | negative regulation of binding | second-messenger-mediated signaling | regulation of cellular protein metabolic process | eating behavior | negative regulation of multicellular organism growth | carbohydrate metabolic process | cell communication | negative regulation of protein binding | regulation of cellular metabolic process | cyclic-nucleotide-mediated signaling | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | regulation of protein phosphorylation | regulation of tube size | negative adaptation of signaling pathway | activation of adenylate cyclase activity | positive regulation of protein modification process | regulation of growth | cAMP-mediated signaling | import into cell | regulation of intracellular signal transduction | vasodilation | metabolic process | oxidation-reduction process | regulation of tube diameter | endocytosis | behavior | organic substance metabolic process | desensitization of G-protein coupled receptor protein signaling pathway | regulation of phosphate metabolic process | positive regulation of MAPK cascade | temperature homeostasis | desensitization of G-protein coupled receptor protein signaling pathway by arrestin | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | feeding behavior | regulation of protein binding | negative regulation of systemic arterial blood pressure | energy reserve metabolic process | regulation of developmental growth | positive regulation of phosphorylation | regulation of developmental process | receptor-mediated endocytosis | regulation of G-protein coupled receptor protein signaling pathway | energy derivation by oxidation of organic compounds | developmental process | norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure | adrenergic receptor signaling pathway | heat generation | response to dietary excess | positive regulation of metabolic process | cellular metabolic process | positive regulation of blood vessel diameter | aging | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | intracellular organelle | receptor complex | protein-containing complex | plasma membrane | integral component of plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | membrane | intrinsic component of plasma membrane