QuickView for AGPS;jsessionid=583065620E0EA563108DD8AC19DC7E21 (gene)

Gene Symbol:

AGPS Homo sapiens

Full name:

alkylglycerone phosphate synthase

Synonyms:

ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY, RCDP3, alkyldihydroxyacetonephosphate synthase, peroxisomal, aging-associated gene 5 protein, aging-associated protein 5, alkyl-DHAP synthase

Genomic Location:

Chr 2: 177965731-178112411

Description:

This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to t...

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This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF4ALPHA_Q6 ,  PPARG_01 ,  COUP_01 ,  TGACCTY_ERR1_Q2 ,  HNF4_DR1_Q3 ,  GGGAGGRR_MAZ_Q6 ,  CAGGTA_AREB6_01 ,  DR1_Q3 ,  COUP_DR1_Q6 ,  PPAR_DR1_Q2 ,  ER_Q6 ,  HNF4_01_B

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Cytogenetic Map:

2q31.2

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