QuickView for AGTR2;jsessionid=88BFBC24181686B5F95C308A74B592B1 (gene)

Gene Symbol:

AGTR2 Homo sapiens

Full name:

angiotensin II receptor type 2

Synonyms:

AT2, ATGR2, MRX88, type-2 angiotensin II receptor, angiotensin II type-2 receptor

Genomic Location:

Chr X: 115215986-115220253

Description:

The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and...

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The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked cognitive disability.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  HNF1_01 ,  NFAT_Q6 ,  YATTNATC_UNKNOWN ,  WGTTNNNNNAAA_UNKNOWN ,  TTTNNANAGCYR_UNKNOWN ,  YYCATTCAWW_UNKNOWN ,  TTCYRGAA_UNKNOWN ,  POU3F2_02 ,  TTGTTT_FOXO4_01 ,  TGCTTTG_MIR330 ,  TGATTTRY_GFI1_01 ,  YNGTTNNNATT_UNKNOWN ,  HNF1_Q6 ,  GTTRYCATRR_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-330

Cytogenetic Map:

Xq23

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