QuickView for AHR (gene)

Gene Symbol:

AHR Homo sapiens

Full name:

aryl hydrocarbon receptor

Synonyms:

bHLHe76, aryl hydrocarbon receptor, AH-receptor, ah receptor, aromatic hydrocarbon receptor, class E basic helix-loop-helix protein 76

Genomic Location:

Chr 7: 17304832-17352299

Description:

The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm;...

View Full Description

The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGIF_01 ,  MAZR_01 ,  AP3_Q6 ,  ATF4_Q2 ,  ACTTTAT_MIR1425P ,  CATTTCA_MIR203 ,  CAGGTG_E12_Q6 ,  TGCCTTA_MIR124A ,  CREB_02 ,  GGGCGGR_SP1_Q6 ,  AREB6_03 ,  GTGCCTT_MIR506 ,  ATATGCA_MIR448 ,  RGAGGAARY_PU1_Q6 ,  TGACAGNY_MEIS1_01 ,  CACBINDINGPROTEIN_Q6 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  GGGTGGRR_PAX4_03

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-375 ,  Predicted Gene Targets for miR-505

miRNA binding sites
(Source: miRecords):

hsa-miR-124 Targeted Genes

Cytogenetic Map:

7p21.1

search → result