QuickView for AHRR;jsessionid=402B4933CA5B757CAE76F7EB9CBFFBCE (gene)
- Gene Symbol:
- AHRR
Homo sapiens - Full name:
- aryl-hydrocarbon receptor repressor
- Synonyms:
- AHH, AHHR, bHLHe77, aryl hydrocarbon receptor repressor, ahR repressor, aryl hydrocarbon hydroxylase regulator, class E basic helix-loop-helix protein 77, dioxin receptor repressor
- Genomic Location:
- Chr 5: 357291-491406
- Description:
-
The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isofo...
- Orthologs:
- Mus musculus , Rattus norvegicus , Danio rerio
- External Links:
- Entrez Gene
- miRNA binding sites
(Source: miRecords):
- Cytogenetic Map:
-
5p15.33
GO Molecular Function
RNA polymerase II transcription factor activity, sequence-specific DNA binding | nucleic acid binding | DNA binding | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | protein dimerization activity | heterocyclic compound binding
GO Biological Process
RNA metabolic process | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cellular process | negative regulation of nucleic acid-templated transcription | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | xenobiotic metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | cellular response to xenobiotic stimulus | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | response to xenobiotic stimulus | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | negative regulation of transcription by RNA polymerase II | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
