QuickView for AK4 (gene)

Gene Symbol:

AK4 Homo sapiens

Full name:

adenylate kinase 4

Synonyms:

AK 4, AK3, AK3L1, AK3L2, adenylate kinase 4, mitochondrial, ATP-AMP transphosphorylase, GTP:AMP phosphotransferase AK4, mitochondrial, adenylate kinase 3-like 1, adenylate kinase isoenzyme 4, mitochondrial, mitochondrial adenylate kinase-3, nucleoside-triphosphate-adenylate kinase

Genomic Location:

Chr 1: 65385820-65465765

Description:

This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been ide...

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This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CAGTGTT_MIR141_MIR200A ,  SCGGAAGY_ELK1_02 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-503 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-140

Cytogenetic Map:

1p31.3

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