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QuickView for AKR1A1 (gene)


Gene Symbol:
AKR1A1 Homo sapiens Homo sapiens
Full name:
aldo-keto reductase family 1 member A1
Synonyms:
ALDR1, ALR, ARM, DD3, HEL-S-6, alcohol dehydrogenase [NADP(+)], HEL-S-165mP, alcohol dehydrogenase, aldehyde reductase, dihydrodiol dehydrogenase 3, epididymis secretory protein Li 6, epididymis secretory sperm binding protein Li 165mP
Genomic Location:
Chr 1: 45789085-45808308
Description:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1p34.1





GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | alcohol dehydrogenase (NADP+) activity | aldo-keto reductase (NADP) activity | catalytic activity | L-glucuronate reductase activity | electron transfer activity | alditol:NADP+ 1-oxidoreductase activity | protein binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | oxidoreductase activity

GO Biological Process

oxidoreductase activity, acting on CH-OH group of donors | vitamin biosynthetic process | sulfur compound metabolic process | D-glucuronate catabolic process | glucose metabolic process | generation of precursor metabolites and energy | glutathione derivative biosynthetic process | cellular process | organic substance catabolic process | carbohydrate catabolic process | catabolic process | alcohol dehydrogenase (NADP+) activity | monocarboxylic acid metabolic process | carboxylic acid catabolic process | aldo-keto reductase (NADP) activity | electron transport chain | L-ascorbic acid biosynthetic process | carbohydrate derivative biosynthetic process | cofactor metabolic process | cellular biosynthetic process | L-glucuronate reductase activity | nitrogen compound metabolic process | coenzyme biosynthetic process | phosphorus metabolic process | electron transfer activity | organophosphate metabolic process | cofactor biosynthetic process | monosaccharide metabolic process | small molecule metabolic process | glucuronate metabolic process | carbohydrate biosynthetic process | biosynthetic process | alditol:NADP+ 1-oxidoreductase activity | carbohydrate metabolic process | phosphate-containing compound metabolic process | L-ascorbic acid metabolic process | glucuronate catabolic process to xylulose 5-phosphate | carboxylic acid metabolic process | cellular aldehyde metabolic process | vitamin metabolic process | metabolic process | hexose metabolic process | oxidation-reduction process | organic substance metabolic process | organic acid metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | aldehyde catabolic process | carbohydrate derivative metabolic process | cellular metabolic process | oxidoreductase activity

GO Cellular Component

apical plasma membrane | cell | cytoplasm | apical part of cell | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | cytosol | intracellular | membrane