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QuickView for AKT3 (gene)


Gene Symbol:
AKT3 Homo sapiens Homo sapiens
Full name:
AKT serine/threonine kinase 3
Synonyms:
MPPH, MPPH2, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2, RAC-gamma serine/threonine-protein kinase, PKB gamma, RAC-gamma serine/threonine protein kinase, v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
Genomic Location:
Chr 1: 241718158-242073176
Description:
The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1q43-q44





GO Molecular Function

ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding

GO Biological Process

brain development | positive regulation of locomotion | intracellular signal transduction | homeostasis of number of cells within a tissue | regulation of localization | peptidyl-amino acid modification | regulation of cell aging | negative regulation of cellular process | positive regulation of developmental process | positive regulation of epithelial cell proliferation | nervous system development | regulation of sprouting angiogenesis | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | tissue homeostasis | cellular process | regulation of cell motility | anatomical structure homeostasis | regulation of angiogenesis | regulation of cellular process | cellular component organization | positive regulation of epithelial cell migration | head development | regulation of vasculature development | response to stimulus | positive regulation of vascular endothelial cell proliferation | regulation of cell proliferation | multicellular organismal homeostasis | protein serine/threonine kinase activity | positive regulation of sprouting angiogenesis | positive regulation of blood vessel endothelial cell migration | brain morphogenesis | regulation of cellular component size | protein modification process | mitochondrion organization | macromolecule modification | regulation of TOR signaling | regulation of cellular response to stress | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | phosphorus metabolic process | animal organ morphogenesis | regulation of cell migration | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of cell migration involved in sprouting angiogenesis | regulation of endothelial cell migration | homeostasis of number of cells | positive regulation of cell migration | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | mitochondrial genome maintenance | positive regulation of signal transduction | positive regulation of TOR signaling | homeostatic process | positive regulation of cell proliferation | regulation of locomotion | protein metabolic process | regulation of intracellular signal transduction | anatomical structure development | metabolic process | protein kinase activity | positive regulation of artery morphogenesis | organic substance metabolic process | animal organ development | regulation of endothelial cell proliferation | negative regulation of cell aging | positive regulation of endothelial cell migration | regulation of epithelial cell migration | regulation of cell communication | regulation of blood vessel endothelial cell migration | negative regulation of cellular senescence | signaling | positive regulation of cell migration involved in sprouting angiogenesis | regulation of epithelial cell proliferation | cellular protein metabolic process | regulation of cell size | anatomical structure morphogenesis | regulation of developmental process | kinase activity | developmental process | organelle organization | peptidyl-serine phosphorylation | positive regulation of cell size | cellular protein modification process | central nervous system development | cellular metabolic process | positive regulation of cell motility | positive regulation of angiogenesis | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of cellular senescence | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular | membrane