Correlation Engine 2.0
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QuickView for ALG8 (gene)

Gene Symbol:
ALG8 Homo sapiens Homo sapiens
Full name:
ALG8, alpha-1,3-glucosyltransferase
CDG1H, probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, HUSSY-02, asparagine-linked glycosylation 8 alpha-13-glucosyltransferase-like protein, asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase), asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase), asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog, asparagine-linked glycosylation protein 8 homolog, dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase, dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, dolichyl-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichol alpha- 1->3-glucosyltransferase, dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase, dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl-alpha-1,3-glucosyltransferase
Genomic Location:
Chr 11: 77489636-77528347
This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively s...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11

GO Molecular Function

dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity | catalytic activity | alpha-1,3-mannosyltransferase activity | glucosyltransferase activity | transferase activity, transferring glycosyl groups | protein binding | transferase activity, transferring hexosyl groups | transferase activity | mannosyltransferase activity | dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity

GO Biological Process

oligosaccharide-lipid intermediate biosynthetic process | cellular process | glycoprotein biosynthetic process | cellular lipid metabolic process | carbohydrate derivative biosynthetic process | protein modification process | macromolecule glycosylation | cellular biosynthetic process | macromolecule modification | dolichol-linked oligosaccharide biosynthetic process | alpha-1,3-mannosyltransferase activity | nitrogen compound metabolic process | lipid metabolic process | biosynthetic process | mannosylation | protein metabolic process | metabolic process | organic substance metabolic process | mannosyltransferase activity | dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity | cellular protein metabolic process | protein N-linked glycosylation | cellular macromolecule biosynthetic process | cellular protein modification process | carbohydrate derivative metabolic process | protein glycosylation | glycosylation | cellular metabolic process | glycoprotein metabolic process | macromolecule metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane