Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for AMPK (gene)


Gene Symbol:
PRKAB1 Homo sapiens Homo sapiens
Full name:
protein kinase AMP-activated non-catalytic subunit beta 1
Synonyms:
AMPK, HAMPKb, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase beta-1 subunit, AMP-activated protein kinase beta subunit, AMPK beta -1 chain, AMPK beta 1, AMPK subunit beta-1, AMPKb, protein kinase, AMP-activated, beta 1 non-catalytic subunit, protein kinase, AMP-activated, noncatalytic, beta-1
Genomic Location:
Chr 12: 118590144-118603812
Description:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activate...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 12
12q24.23


Transcripts Names
NM_006253
XM_005253909



GO Molecular Function

kinase binding | protein kinase binding | enzyme binding | protein serine/threonine kinase activity | catalytic activity | AMP-activated protein kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | kinase activity

GO Biological Process

limb development | macroautophagy | negative regulation of cellular process | cellular process | regulation of cell cycle | regulation of cellular process | regulation of metabolic process | catabolic process | cellular component organization | cellular lipid metabolic process | response to stimulus | nail development | monocarboxylic acid metabolic process | positive regulation of cold-induced thermogenesis | protein serine/threonine kinase activity | cellular component assembly | protein modification process | cellular biosynthetic process | macromolecule modification | nitrogen compound metabolic process | multicellular organism development | phosphorus metabolic process | protein complex oligomerization | regulation of catalytic activity | lipid metabolic process | regulation of gene expression | cell cycle | AMP-activated protein kinase activity | small molecule metabolic process | fatty acid biosynthetic process | biosynthetic process | phosphorylation | lipid biosynthetic process | protein phosphorylation | phosphate-containing compound metabolic process | autophagy | cell communication | carboxylic acid metabolic process | protein-containing complex assembly | protein metabolic process | cell cycle arrest | anatomical structure development | metabolic process | protein kinase activity | organic substance metabolic process | fatty acid metabolic process | negative regulation of cell cycle | signaling | organic acid metabolic process | cellular protein metabolic process | protein heterooligomerization | kinase activity | developmental process | cellular protein modification process | positive regulation of metabolic process | cellular metabolic process | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | protein kinase complex | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | transferase complex | membrane-bounded organelle | nucleus | organelle | nucleotide-activated protein kinase complex | membrane-enclosed lumen | cytosol | intracellular