QuickView for ANG (gene)

Gene Symbol:

ANG Homo sapiens

Full name:

angiogenin

Synonyms:

ALS9, HEL168, RAA1, RNASE4, RNASE5, angiogenin, RNase 5, angiogenin, ribonuclease, RNase A family, 5, epididymis luminal protein 168, ribonuclease 5, ribonuclease A A1, ribonuclease A family member 5

Genomic Location:

Chr 14: 20222176-20232185

Description:

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Altern...

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The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YATGNWAAT_OCT_C

Cytogenetic Map:

14q11.2

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