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QuickView for ANGII (gene)


Gene Symbol:
Agt Mus musculus Mus musculus
Full name:
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Synonyms:
AI265500, AngI, AngII, Aogen, Serpina8, angiotensinogen, angiotensin I, angiotensin ll, serpin A8
Genomic Location:
Chr 8: 127080487-127093607
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Canis lupus familiaris Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_007428
Protein Names
Q3UTR7



GO Molecular Function

endopeptidase inhibitor activity | type 1 angiotensin receptor binding | enzyme inhibitor activity | signaling receptor binding | hormone activity | molecular function regulator | angiotensin receptor binding | type 2 angiotensin receptor binding | protein binding | receptor regulator activity | G-protein coupled receptor binding | receptor ligand activity | serine-type endopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity

GO Biological Process

positive regulation of smooth muscle cell proliferation | regulation of neurotrophin TRK receptor signaling pathway | regulation of blood vessel diameter | regulation of muscle system process | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | endopeptidase inhibitor activity | regulation of systemic arterial blood pressure by hormone | regulation of transmission of nerve impulse | extracellular structure organization | positive regulation of cellular component organization | regulation of neurogenesis | developmental process involved in reproduction | muscle tissue development | intracellular signal transduction | endothelial cell development | positive regulation of apoptotic process | regulation of cell development | regulation of localization | cell-substrate adhesion | morphogenesis of an epithelium | gonad development | regulation of programmed cell death | vascular smooth muscle contraction | positive regulation of peptidyl-tyrosine phosphorylation | female gonad development | smooth muscle cell differentiation | establishment of localization | regulation of nitric oxide biosynthetic process | astrocyte development | negative regulation of neuron death | cell growth involved in cardiac muscle cell development | negative regulation of cellular process | positive regulation of developmental process | regulation of cardiac muscle cell apoptotic process | cell differentiation | negative regulation of tissue remodeling | positive regulation of fibroblast proliferation | endothelial cell differentiation | striated muscle cell development | nervous system development | regulation of extracellular matrix organization | organ growth | cellular chemical homeostasis | neurogenesis | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | tonic smooth muscle contraction | regulation of renal sodium excretion | generation of neurons | positive regulation of protein secretion | cardiac cell development | intracellular transport | regulation of lipid transport | negative regulation of proteolysis | fibroblast proliferation | positive regulation of vascular smooth muscle cell proliferation | regulation of neuron death | artery smooth muscle contraction | positive regulation of cellular biosynthetic process | cellular process | secretion | peripheral nervous system development | regulation of catecholamine secretion | regulation of glucose import | regulation of cell motility | localization | cellular homeostasis | epithelial tube morphogenesis | protein transport | negative regulation of signaling | developmental growth | positive regulation of peptidyl-serine phosphorylation | positive regulation of reactive oxygen species metabolic process | regulation of neuronal synaptic plasticity | reproductive system development | cellular sodium ion homeostasis | multicellular organismal reproductive process | learning | renal tubule morphogenesis | positive regulation of protein kinase activity | macromolecule localization | negative regulation of apoptotic process | branching involved in ureteric bud morphogenesis | regulation of proteolysis | positive regulation of catalytic activity | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | positive regulation of muscle cell apoptotic process | activation of phospholipase C activity | establishment of localization in cell | negative regulation of cellular metabolic process | tissue development | regulation of neurological system process | regulation of cell differentiation | gamete generation | positive regulation of cardiac muscle hypertrophy | drinking behavior | muscle structure development | muscle cell differentiation | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | gliogenesis | positive regulation of extracellular matrix constituent secretion | regulation of cytosolic calcium ion concentration | positive regulation of extracellular matrix organization | protein import into nucleus | neurological system process involved in regulation of systemic arterial blood pressure | regulation of renal output by angiotensin | positive regulation of cellular protein metabolic process | epithelium development | positive regulation of renal sodium excretion | smooth muscle contraction | cellular component organization | angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure | MAPK cascade | regulation of systemic arterial blood pressure mediated by a chemical signal | calcium ion homeostasis | urogenital system development | positive regulation of epithelial cell migration | nephron tubule morphogenesis | development of primary sexual characteristics | regulation of peptide secretion | muscle contraction | associative learning | regulation of vasculature development | response to stimulus | enzyme inhibitor activity | positive regulation of blood pressure | ovulation | vasculature development | muscle cell development | female gamete generation | positive regulation of NIK/NF-kappaB signaling | regulation of fatty acid biosynthetic process | regulation of peptidyl-tyrosine phosphorylation | positive regulation of nitric oxide metabolic process | regulation of excretion | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | regulation of blood vessel size | response to cold | regulation of norepinephrine secretion | response to salt stress | positive regulation of phosphatidylinositol 3-kinase signaling | response to stress | intracellular protein transport | positive regulation of cation transmembrane transport | renin-angiotensin regulation of aldosterone production | positive regulation of JAK-STAT cascade | regulation of activation of Janus kinase activity | regulation of response to drug | regulation of cell proliferation | positive regulation of lipid biosynthetic process | ovulation cycle | negative regulation of angiogenesis | positive regulation of gap junction assembly | tube morphogenesis | regulation of blood circulation | cardiac muscle tissue development | protein localization to nucleus | positive regulation of glucose import | epithelial cell development | positive regulation of protein kinase C activity | regulation of smooth muscle cell migration | development of primary female sexual characteristics | physiological cardiac muscle hypertrophy | peristalsis | regulation of heart rate | reproduction | cellular localization | secretion by cell | positive regulation of superoxide anion generation | positive regulation of cytokine secretion | cardiovascular system development | response to temperature stimulus | rhythmic process | regulation of cholesterol esterification | positive regulation of lipase activity | extracellular matrix organization | hormone activity | regulation of protein transport | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | protein modification process | regulation of peptide transport | modulation of chemical synaptic transmission | kidney development | positive regulation of multicellular organism growth | heart growth | regulation of morphogenesis of a branching structure | ovulation from ovarian follicle | macromolecule modification | regulation of steroid metabolic process | activation of protein kinase activity | positive regulation of ERBB signaling pathway | molecular function regulator | metal ion homeostasis | blood vessel development | stress-activated protein kinase signaling cascade | negative regulation of blood vessel diameter | positive regulation of vascular associated smooth muscle cell migration | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | regulation of neurotransmitter levels | positive regulation of phospholipase C activity | negative regulation of neuron apoptotic process | regulation of long-term neuronal synaptic plasticity | positive regulation of reactive oxygen species biosynthetic process | regulation of protein tyrosine kinase activity | positive regulation of cell junction assembly | regulation of superoxide metabolic process | system development | sodium ion homeostasis | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | endothelium development | ureteric bud development | negative regulation of growth | positive regulation of neuron projection development | astrocyte activation | multicellular organism development | negative regulation of catalytic activity | response to activity | regulation of peptidase activity | regulation of MAPK cascade | phosphorus metabolic process | learning or memory | positive regulation of smooth muscle cell migration | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | kidney morphogenesis | regulation of hormone levels | regulation of hormone secretion | negative regulation of peptidase activity | positive regulation of glucose import in response to insulin stimulus | regulation of neuron differentiation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | kidney epithelium development | positive regulation of secretion | organic substance transport | cellular response to stress | nervous system process | regulation of blood pressure | excretion | regulation of glucose import in response to insulin stimulus | regulation of systemic arterial blood pressure by renin-angiotensin | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | animal organ morphogenesis | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of cell projection organization | positive regulation of STAT cascade | peptide transport | negative regulation of cellular response to growth factor stimulus | positive regulation of intracellular signal transduction | cardiocyte differentiation | regulation of cellular component movement | protein localization to organelle | positive regulation of hydrolase activity | import into nucleus | regulation of fatty acid metabolic process | positive regulation of cell differentiation | regulation of endothelial cell migration | cognition | positive regulation of steroid metabolic process | positive regulation of cell migration | positive regulation of glucose transmembrane transport | cell proliferation | cardiac muscle hypertrophy | response to osmotic stress | stress-activated MAPK cascade | regulation of cellular protein metabolic process | cardiac muscle cell development | glial cell differentiation | vasoconstriction | regulation of blood volume by renin-angiotensin | phosphorylation | mesonephric epithelium development | regulation of phospholipase activity | positive regulation of L-lysine import across plasma membrane | positive regulation of fatty acid biosynthetic process | regulation of apoptotic signaling pathway | regulation of heart contraction | activation of NF-kappaB-inducing kinase activity | protein phosphorylation | mesonephros development | cation homeostasis | phosphate-containing compound metabolic process | positive regulation of cellular response to insulin stimulus | ovulation cycle process | protein import | regulation of muscle cell apoptotic process | striated muscle tissue development | peptide secretion | cellular cation homeostasis | endocrine process | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of response to drug | regulation of neuron apoptotic process | renal tubule development | astrocyte differentiation | regulation of endocrine process | regulation of NIK/NF-kappaB signaling | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cholesterol esterification | heart development | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | renal system development | regulation of tube size | positive regulation of transport | regulation of lipid biosynthetic process | striated muscle cell differentiation | negative regulation of cell growth | regulation of cellular response to growth factor stimulus | positive regulation of systemic arterial blood pressure | nephron development | cardiac muscle tissue growth | regulation of phospholipase C activity | positive regulation of molecular function | regulation of cytokine secretion | multicellular organism reproduction | cytokine production | regulation of signaling receptor activity | receptor regulator activity | ureteric bud morphogenesis | positive regulation of organ growth | protein metabolic process | regulation of fibroblast proliferation | regulation of cardiac muscle hypertrophy | regulation of establishment of protein localization | angiotensin-mediated drinking behavior | positive regulation of protein modification process | regulation of growth | tissue morphogenesis | branching morphogenesis of an epithelial tube | regulation of JAK-STAT cascade | regulation of kinase activity | regulation of animal organ morphogenesis | positive regulation of fatty acid metabolic process | regulation of intracellular signal transduction | establishment of protein localization to organelle | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | vasodilation | metabolic process | positive regulation of cell development | cytokine secretion | positive regulation of branching involved in ureteric bud morphogenesis | regulation of RNA biosynthetic process | negative regulation of programmed cell death | smooth muscle cell proliferation | regulation of tube diameter | cellular protein localization | regulation of tissue remodeling | amide transport | chemical homeostasis | brain renin-angiotensin system | regulation of secretion | behavior | positive regulation of cell death | cell adhesion | receptor ligand activity | positive regulation of cellular component biogenesis | organic substance metabolic process | regulation of epidermal growth factor receptor signaling pathway | nuclear transport | regulation of extracellular matrix assembly | nephron morphogenesis | regulation of glucose transmembrane transport | positive regulation of amino acid transport | animal organ development | positive regulation of ion transport | negative regulation of cellular protein metabolic process | regulation of protein secretion | positive regulation of programmed cell death | establishment of blood-nerve barrier | ovarian follicle rupture | positive regulation of kinase activity | ion homeostasis | regulation of cellular response to insulin stimulus | negative regulation of neurotrophin TRK receptor signaling pathway | regulation of phosphate metabolic process | regulation of ion transmembrane transport | renal system process | regulation of systemic arterial blood pressure by circulatory renin-angiotensin | positive regulation of organic acid transport | establishment of protein localization | response to muscle activity involved in regulation of muscle adaptation | positive regulation of cytokine production | serine-type endopeptidase inhibitor activity | positive regulation of phospholipase activity | positive regulation of endothelial cell migration | cell activation | positive regulation of MAPK cascade | morphogenesis of a branching epithelium | positive regulation of protein transport | regulation of reactive oxygen species biosynthetic process | regulation of peptidyl-serine phosphorylation | positive regulation of cardiac muscle cell apoptotic process | regulation of L-arginine import | negative regulation of protein metabolic process | regulation of epithelial cell migration | cardiac muscle cell differentiation | regulation of cell communication | negative regulation of molecular function | muscle cell proliferation | negative regulation of signal transduction | positive regulation of developmental growth | signaling | feeding behavior | positive regulation of growth | regulation of transcription, DNA-templated | cell-matrix adhesion | glial cell development | cellular monovalent inorganic cation homeostasis | cell development | regulation of ERBB signaling pathway | regulation of developmental growth | positive regulation of L-arginine import across plasma membrane | protein localization | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | peptidase inhibitor activity | cellular protein metabolic process | enzyme regulator activity | positive regulation of epidermal growth factor receptor signaling pathway | regulation of cytokine production | hormone metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | regulation of endopeptidase activity | cellular macromolecule localization | operant conditioning | regulation of organ growth | nucleocytoplasmic transport | reproductive structure development | regulation of cellular ketone metabolic process | regulation of nervous system development | regulation of developmental process | regulation of ion transport | renal system process involved in regulation of systemic arterial blood pressure | developmental process | positive regulation of anion transport | regulation of cell growth | regulation of cardiac conduction | regulation of calcium ion transport | cellular protein modification process | tube development | regulation of cell junction assembly | regulation of transport | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | negative regulation of cell proliferation | developmental cell growth | regulation of superoxide anion generation | negative regulation of vasculature development | positive regulation of kidney development | positive regulation of nucleic acid-templated transcription | cellular metal ion homeostasis | epithelial cell differentiation | ERK1 and ERK2 cascade | NIK/NF-kappaB signaling | negative regulation of hydrolase activity | regulation of anion transport | positive regulation of nitric oxide biosynthetic process | regulation of branching involved in ureteric bud morphogenesis | central nervous system development | regulation of lipid metabolic process | positive regulation of metabolic process | regulation of synaptic plasticity | positive regulation of neuron differentiation | positive regulation of lipid metabolic process | regulation of cell projection organization | cellular metabolic process | female sex differentiation | regulation of protein localization | regulation of cell death | sex differentiation | protein secretion | regulation of smooth muscle cell proliferation | positive regulation of cell motility | regulation of blood vessel diameter by renin-angiotensin | negative regulation of cell death | renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure | positive regulation of blood vessel diameter | circulatory system development | regulation of inflammatory response | uterine smooth muscle contraction | muscle hypertrophy | divalent inorganic cation homeostasis | sexual reproduction | nephron tubule development | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | muscle system process | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | negative regulation of endopeptidase activity | mesonephric tubule development | response to muscle activity | positive regulation of gene expression | positive regulation of activation of Janus kinase activity | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

cell | cytoplasm | extracellular region | extracellular space | intracellular