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QuickView for AP-1 (gene)


Gene Symbol:
JUN Canis lupus familiaris Canis lupus familiaris
Full name:
jun oncogene
Synonyms:
AP-1
Genomic Location:
Chr 5: 53969418-53971089
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
AACTTT_UNKNOWN MEF2_01 IK1_01 GATA1_02 GATA1_03 GATA1_04 HSF1_01 HSF2_01 CEBP_C GATA_C


Protein Names
E2R6T4



GO Molecular Function

sequence-specific DNA binding | enzyme activator activity | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enhancer binding | GTPase activator activity | proximal promoter sequence-specific DNA binding | enzyme binding | RNA polymerase II activating transcription factor binding | nucleic acid binding | GTPase regulator activity | molecular function regulator | chromatin binding | ubiquitin-like protein ligase binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | identical protein binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | transcription factor binding | ubiquitin protein ligase binding | RNA polymerase II transcription factor binding | activating transcription factor binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | cAMP response element binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | enzyme regulator activity | SMAD binding | heterocyclic compound binding | R-SMAD binding

GO Biological Process

RNA metabolic process | positive regulation of smooth muscle cell proliferation | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | SMAD protein signal transduction | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | response to endoplasmic reticulum stress | positive regulation of cellular component organization | intracellular signal transduction | enzyme activator activity | positive regulation of apoptotic process | regulation of localization | regulation of programmed cell death | eye development | myeloid cell differentiation | negative regulation of neuron death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | response to metal ion | cell differentiation | positive regulation of epithelial cell proliferation | positive regulation of fibroblast proliferation | nervous system development | negative regulation of protein phosphorylation | neurogenesis | positive regulation of phosphate metabolic process | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | generation of neurons | interaction with symbiont | blood vessel morphogenesis | positive regulation of vascular smooth muscle cell proliferation | regulation of neuron death | positive regulation of GTPase activity | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | heart morphogenesis | neuron development | immune system development | negative regulation of nucleic acid-templated transcription | GTPase activator activity | negative regulation of apoptotic process | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | negative regulation of cellular metabolic process | tissue development | regulation of binding | interspecies interaction between organisms | regeneration | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | positive regulation by host of viral transcription | regulation of protein complex assembly | hepaticobiliary system development | small GTPase mediated signal transduction | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | negative regulation of protein autophosphorylation | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | response to transforming growth factor beta | cellular response to metal ion | positive regulation of epithelial cell migration | response to stimulus | vasculature development | positive regulation of protein metabolic process | GTPase regulator activity | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | response to muscle stretch | cellular response to inorganic substance | cardiovascular system development | cellular response to cadmium ion | cellular nitrogen compound metabolic process | regulation of DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | cellular biosynthetic process | molecular function regulator | blood vessel development | regulation of nucleic acid-templated transcription | leukocyte differentiation | negative regulation of neuron apoptotic process | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | positive regulation of viral process | multicellular organism development | regulation of MAPK cascade | negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | regulation of catalytic activity | cellular response to oxidative stress | regulation of phosphorylation | monocyte differentiation | regulation of gene expression | axon development | outflow tract morphogenesis | cellular response to stress | regulation of protein autophosphorylation | myeloid leukocyte differentiation | modification of morphology or physiology of other organism | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | eyelid development in camera-type eye | response to axon injury | animal organ morphogenesis | regulation of pri-miRNA transcription by RNA polymerase II | liver development | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | negative regulation of DNA binding | positive regulation of protein complex assembly | regulation of cellular component movement | regulation of transcription by RNA polymerase II | response to oxidative stress | negative regulation of binding | positive regulation of hydrolase activity | negative regulation of viral process | positive regulation of cell migration | biosynthetic process | response to cadmium ion | neuron projection regeneration | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | angiogenesis | positive regulation of pri-miRNA transcription by RNA polymerase II | regulation of GTPase activity | microglial cell activation | sensory organ development | negative regulation by host of viral transcription | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of neuron apoptotic process | regulation of protein metabolic process | positive regulation of signal transduction | heart development | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | regulation of viral process | positive regulation of molecular function | cellular response to transforming growth factor beta stimulus | neuron differentiation | regulation of fibroblast proliferation | DNA-binding transcription factor activity | positive regulation of protein modification process | cellular response to calcium ion | response to organic substance | gland development | response to wounding | response to mechanical stimulus | positive regulation of viral transcription | leading edge cell differentiation | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | regulation of DNA-templated transcription in response to stress | positive regulation of DNA-templated transcription, initiation | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | macrophage activation | nucleobase-containing compound metabolic process | cellular response to reactive oxygen species | neuron projection development | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | response to reactive oxygen species | regulation of endothelial cell proliferation | negative regulation of cellular protein metabolic process | gene expression | positive regulation of ERK1 and ERK2 cascade | positive regulation of programmed cell death | negative regulation of transcription from RNA polymerase II promoter in response to stress | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | regulation of phosphate metabolic process | transcription, DNA-templated | cell activation | positive regulation of MAPK cascade | camera-type eye development | modulation by host of viral transcription | transforming growth factor beta receptor signaling pathway | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | regulation of epithelial cell migration | regulation of cell communication | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | cell development | regulation of epithelial cell proliferation | positive regulation of phosphorylation | enzyme regulator activity | regulation of transcription from RNA polymerase II promoter in response to stress | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of DNA-templated transcription, initiation | axon regeneration | developmental process | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | Ras protein signal transduction | positive regulation of nucleic acid-templated transcription | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | response to calcium ion | regulation of viral transcription | positive regulation of metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of cell death | regulation of smooth muscle cell proliferation | positive regulation of cell motility | negative regulation of cell death | circulatory system development | negative regulation of viral transcription | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

nuclear euchromatin | nuclear transcription factor complex | chromosome | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | euchromatin | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | membrane-bounded organelle | transcriptional repressor complex | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | transcription factor AP-1 complex | intracellular