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QuickView for AP1G1;jsessionid=C6500214117C5AE20D078D4E44D41258 (gene)


Gene Symbol:
AP1G1 Homo sapiens Homo sapiens
Full name:
adaptor related protein complex 1 gamma 1 subunit
Synonyms:
ADTG, CLAPG1, AP-1 complex subunit gamma-1, adapter-related protein complex 1 subunit gamma-1, adaptor protein complex AP-1 subunit gamma-1, adaptor-related protein complex 1 subunit gamma-1, clathrin assembly protein complex 1 gamma large chain, clathrin assembly protein complex 1 gamma-1 large chain, clathrin-associated/assembly/adaptor protein, large, gamma 1, gamma adaptin, gamma1-adaptin, golgi adaptor HA1/AP1 adaptin gamma subunit, golgi adaptor HA1/AP1 adaptin subunit gamma-1, testicular tissue protein Li 21
Genomic Location:
Chr 16: 70320404-70400477
Description:
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, fo...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
TGGAAA_NFAT_Q4_01 TTTGCAC_MIR19A_MIR19B CCCACAT_MIR2993P GGGATGC_MIR3245P TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D TGANNYRGCA_TCF11MAFG_01 TTTTGAG_MIR373 CTACTGT_MIR199A TTCCGTT_MIR191 NGFIC_01
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-1 Predicted Gene Targets for miR-101 Predicted Gene Targets for miR-130 Predicted Gene Targets for miR-142-5p Predicted Gene Targets for miR-144 Predicted Gene Targets for miR-145 Predicted Gene Targets for miR-148 Predicted Gene Targets for miR-181 Predicted Gene Targets for miR-186 Predicted Gene Targets for miR-19
Cytogenetic Map:
chr 16
16q22.2





GO Molecular Function

GTPase binding | enzyme binding | GTP-dependent protein binding | Ras GTPase binding | cytoskeletal protein binding | kinesin binding | transporter activity | protein binding | small GTPase binding | Rab GTPase binding

GO Biological Process

positive regulation of immune response | positive regulation of cell killing | antigen processing and presentation | regulation of localization | endosome to pigment granule transport | establishment of localization | regulation of immune system process | positive regulation of lymphocyte activation | cell differentiation | regulation of leukocyte mediated cytotoxicity | Golgi to vacuole transport | intracellular transport | melanosome organization | cellular process | localization | protein transport | positive regulation of immune effector process | macromolecule localization | establishment of localization in cell | cytosolic transport | interspecies interaction between organisms | regulation of immune response | regulation of cellular process | regulation of natural killer cell activation | cellular component organization | positive regulation of natural killer cell mediated immunity | response to stimulus | lysosomal transport | positive regulation of innate immune response | pigment accumulation | positive regulation of immune system process | intracellular protein transport | vacuolar transport | pigment granule maturation | endosome to melanosome transport | pigment cell differentiation | positive regulation of cell activation | cellular localization | positive regulation of natural killer cell activation | antigen processing and presentation of exogenous peptide antigen via MHC class II | positive regulation of exocytosis | antigen processing and presentation of peptide antigen via MHC class II | pigment granule organization | post-Golgi vesicle-mediated transport | positive regulation of secretion | organic substance transport | regulation of lymphocyte activation | developmental pigmentation | peptide transport | Golgi to lysosome transport | vesicle-mediated transport | pigmentation | positive regulation of regulated secretory pathway | Golgi vesicle transport | positive regulation of transport | viral process | positive regulation of natural killer cell degranulation | antigen processing and presentation of exogenous antigen | regulation of innate immune response | regulation of exocytosis | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | regulation of defense response to virus by virus | positive regulation of leukocyte activation | developmental maturation | cellular protein localization | amide transport | regulation of vesicle-mediated transport | regulation of secretion | regulation of cell activation | positive regulation of natural killer cell mediated cytotoxicity | establishment of protein localization | vesicle organization | regulation of regulated secretory pathway | regulation of natural killer cell mediated cytotoxicity | protein localization | cellular macromolecule localization | developmental process | organelle organization | cellular pigmentation | regulation of transport | positive regulation of leukocyte mediated cytotoxicity | antigen processing and presentation of peptide antigen | cellular pigment accumulation | immune system process | regulation of natural killer cell mediated immunity

GO Cellular Component

trans-Golgi network membrane | intracellular membrane-bounded organelle | clathrin-coated vesicle membrane | organelle membrane | vesicle coat | clathrin-coated vesicle | cytoplasmic vesicle | Golgi-associated vesicle membrane | cell | transport vesicle membrane | cytoplasm | intracellular organelle | clathrin coat of trans-Golgi network vesicle | AP-type membrane coat adaptor complex | Golgi apparatus | protein-containing complex | clathrin adaptor complex | recycling endosome | endomembrane system | Golgi-associated vesicle | vacuole | vesicle | transport vesicle | lytic vacuole | Golgi membrane | endosome | coated vesicle membrane | membrane-bounded organelle | clathrin coat | organelle | vesicle membrane | lysosome | clathrin vesicle coat | trans-Golgi network | trans-Golgi network transport vesicle membrane | trans-Golgi network transport vesicle | cytosol | intracellular vesicle | intracellular | AP-1 adaptor complex | lysosomal membrane | membrane | cytoplasmic vesicle membrane | membrane coat | vacuolar membrane | coated vesicle